CATH Superfamily 1.20.58.480
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: Indoleamine 2,3-dioxygenase subfamily
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Indoleamine 2,3-dioxygenase activity GO:0033754
Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.
|
6 | P47125 (/IDA) Q2U3U2 (/IDA) Q2U3U2 (/IDA) Q2U3U2 (/IDA) Q2U3U2 (/IDA) Q2UJE7 (/IDA) |
|
Tryptophan 2,3-dioxygenase activity GO:0004833
Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.
|
2 | A0A1D8PN08 (/ISA) A0A1D8PN08 (/ISA) |
|
Tryptophan 2,3-dioxygenase activity GO:0004833
Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.
|
2 | Q5BC72 (/RCA) Q5BC72 (/RCA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tryptophan catabolic process to kynurenine GO:0019441
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
|
5 | Q2U3U2 (/IDA) Q2U3U2 (/IDA) Q2U3U2 (/IDA) Q2U3U2 (/IDA) Q2UJE7 (/IDA) |
|
Aromatic amino acid family biosynthetic process GO:0009073
The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
|
2 | Q5BC72 (/RCA) Q5BC72 (/RCA) |
|
'de novo' NAD biosynthetic process from tryptophan GO:0034354
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
|
2 | A0A1D8PN08 (/ISA) A0A1D8PN08 (/ISA) |
|
Filamentous growth of a population of unicellular organisms in response to chemical stimulus GO:0036171
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
|
2 | A0A1D8PN08 (/IMP) A0A1D8PN08 (/IMP) |
|
Tryptophan catabolic process to kynurenine GO:0019441
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
|
1 | P47125 (/IC) |
|
'de novo' NAD biosynthetic process from tryptophan GO:0034354
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
|
1 | P47125 (/IGI) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P47125 (/HDA) |