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CATH Superfamily 1.20.58.480

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Tryptophan 2,3-dioxygenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tryptophan 2,3-dioxygenase activity GO:0004833
Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.
 186 A0JUV5 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS)
(176 more)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
 186 A0JUV5 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS)
(176 more)
Tryptophan 2,3-dioxygenase activity GO:0004833
Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.
 7 Q1LK00 (/IDA) Q1LK00 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
 7 Q1LK00 (/IDA) Q1LK00 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tryptophan catabolic process to kynurenine GO:0019441
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
 186 A0JUV5 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS)
(176 more)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
 186 A0JUV5 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0KA02 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS) A0REX0 (/ISS)
(176 more)
Tryptophan catabolic process to kynurenine GO:0019441
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
 7 Q1LK00 (/IDA) Q1LK00 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
 5 Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA) Q8PDA8 (/IDA)
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
 2 Q1LK00 (/NAS) Q1LK00 (/NAS)
Quinolinate biosynthetic process GO:0019805
The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
 2 Q1LK00 (/NAS) Q1LK00 (/NAS)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
 2 Q1LK00 (/IDA) Q1LK00 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.