The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Eb1, isoform E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 A1Z6P3 (/IPI) Q7JZD3 (/IPI) Q9XZ57 (/IPI)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
3 A1Z6P3 (/TAS) Q7JZD3 (/TAS) Q9XZ57 (/TAS)
Myosin binding GO:0017022
Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
3 A1Z6P3 (/IPI) Q7JZD3 (/IPI) Q9XZ57 (/IPI)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitotic spindle elongation GO:0000022
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
3 A1Z6P3 (/IDA) Q7JZD3 (/IDA) Q9XZ57 (/IDA)
Mitotic spindle elongation GO:0000022
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
3 A1Z6P3 (/IDA) Q7JZD3 (/IDA) Q9XZ57 (/IDA)
Microtubule-based process GO:0007017
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
3 A1Z6P3 (/TAS) Q7JZD3 (/TAS) Q9XZ57 (/TAS)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
3 A1Z6P3 (/TAS) Q7JZD3 (/TAS) Q9XZ57 (/TAS)
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
3 A1Z6P3 (/IDA) Q7JZD3 (/IDA) Q9XZ57 (/IDA)
Sensory organ development GO:0007423
The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Flight behavior GO:0007629
The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Pseudocleavage involved in syncytial blastoderm formation GO:0030589
Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Establishment or maintenance of microtubule cytoskeleton polarity GO:0030951
Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
3 A1Z6P3 (/TAS) Q7JZD3 (/TAS) Q9XZ57 (/TAS)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
3 A1Z6P3 (/IMP) Q7JZD3 (/IMP) Q9XZ57 (/IMP)
Spindle assembly GO:0051225
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
3 A1Z6P3 (/IDA) Q7JZD3 (/IDA) Q9XZ57 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 A1Z6P3 (/IDA) Q7JZD3 (/IDA) Q9XZ57 (/IDA)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
3 A1Z6P3 (/IDA) Q7JZD3 (/IDA) Q9XZ57 (/IDA)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
3 A1Z6P3 (/TAS) Q7JZD3 (/TAS) Q9XZ57 (/TAS)
Axonal growth cone GO:0044295
The migrating motile tip of a growing nerve cell axon.
1 A1Z6P3 (/IDA)
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