The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Phosphatidic acid phosphatase type 2/haloperoxidase
".
FunFam 7: phospholipid phosphatase 1 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Phosphatidate phosphatase activity GO:0008195
Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.
|
4 | O14494 (/IDA) O14494 (/IDA) O14494 (/IDA) Q61469 (/IDA) |
Phosphatidate phosphatase activity GO:0008195
Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.
|
3 | O08564 (/ISS) O88956 (/ISS) Q61469 (/ISS) |
Phosphatidate phosphatase activity GO:0008195
Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.
|
3 | O14494 (/NAS) O14494 (/NAS) O14494 (/NAS) |
Sphingosine-1-phosphate phosphatase activity GO:0042392
Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.
|
3 | O14494 (/TAS) O14494 (/TAS) O14494 (/TAS) |
Lipid phosphatase activity GO:0042577
Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.
|
3 | O14494 (/IDA) O14494 (/IDA) O14494 (/IDA) |
Phosphatidate phosphatase activity GO:0008195
Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.
|
2 | O08564 (/TAS) Q61469 (/TAS) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
3 | O14494 (/NAS) O14494 (/NAS) O14494 (/NAS) |
Protein kinase C-activating G protein-coupled receptor signaling pathway GO:0007205
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
|
3 | O14494 (/TAS) O14494 (/TAS) O14494 (/TAS) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
3 | O14494 (/NAS) O14494 (/NAS) O14494 (/NAS) |
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
|
3 | O14494 (/TAS) O14494 (/TAS) O14494 (/TAS) |
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
3 | O14494 (/NAS) O14494 (/NAS) O14494 (/NAS) |
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
|
3 | O14494 (/TAS) O14494 (/TAS) O14494 (/TAS) |
Intracellular steroid hormone receptor signaling pathway GO:0030518
A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.
|
3 | O14494 (/TAS) O14494 (/TAS) O14494 (/TAS) |
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
3 | O14494 (/NAS) O14494 (/NAS) O14494 (/NAS) |
Phospholipid dephosphorylation GO:0046839
The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
|
3 | O14494 (/IDA) O14494 (/IDA) O14494 (/IDA) |
Phospholipid dephosphorylation GO:0046839
The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
|
3 | O14494 (/TAS) O14494 (/TAS) O14494 (/TAS) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q61469 (/IDA) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q61469 (/TAS) |
Diacylglycerol biosynthetic process GO:0006651
The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
|
1 | Q61469 (/TAS) |
Sphingosine metabolic process GO:0006670
The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
|
1 | Q61469 (/TAS) |
Ceramide metabolic process GO:0006672
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
|
1 | Q61469 (/TAS) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | Q61469 (/TAS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | O14494 (/TAS) O14494 (/TAS) O14494 (/TAS) Q61469 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O14494 (/NAS) O14494 (/NAS) O14494 (/NAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | O14494 (/IDA) O14494 (/IDA) O14494 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | O08564 (/ISS) O88956 (/ISS) Q61469 (/ISS) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
3 | O14494 (/HDA) O14494 (/HDA) O14494 (/HDA) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
1 | F1N992 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q61469 (/TAS) |