The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: RNA polymerase sigma factor RpoH

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial-type RNA polymerase core promoter sequence-specific DNA binding GO:0000985
Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a bacterial gene.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
172 P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI) P0AGB3 (/IPI)
(162 more)
Site-specific recombinase activity GO:0009009
Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial transcription GO:0001121
The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
Bacterial transcription GO:0001121
The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter.
172 P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM) P0AGB3 (/ISM)
(162 more)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
172 P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP)
(162 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
172 P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP) P0AGB3 (/IEP)
(162 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
172 P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP) P0AGB3 (/IMP)
(162 more)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)
Invertasome GO:0031421
A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.
172 P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA) P0AGB3 (/IDA)
(162 more)