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CATH Superfamily 1.20.1270.60

Arfaptin homology (AH) domain/BAR domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Arfaptin homology (AH) domain/BAR domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Rho GTPase-activating protein 26
702 - - 97.7
2
Formin-binding protein 1-like isoform 1
596
3D
 2efkA01 - 95.4
3
arfaptin-2 isoform X1
584
3D
 4dcnD00 - 84.3
4
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
545 - - 73.7
5
Sphingolipid long chain base-responsive pil1
493
3D
 3pltC00 - 91.8
6
SLIT-ROBO Rho GTPase-activating protein 1 isoform 2
488 - - 92.6
7
Bridging integrator 1, isoform CRA_e
455
3D
 2ficB00 - 76.2
8
Sorting nexin
453 - - 94.3
9
Protein kinase C and casein kinase substrate in neurons 2
444
3D
 3lllB01 - 94.3
10
Metastasis suppressor 1, isoform CRA_e
399
3D
 2d1lB00 - 64.8
11
Brain-specific angiogenesis inhibitor 1-associated protein 2
390
3D
 2yktA00 - 87.7
12
Sorting nexin 2
381
3D
 4fzsB00 - 92.6
13
Amphiphysin isoform 2
369
3D
 4atmA00 - 94.7
14
Protein hob3, variant
347 - - 90.6
16
FCH domain only protein 2
312
3D
 2v0oC00 - 93.9
15
Islet cell autoantigen 1, 69kDa
310 - - 75.4
17
endophilin-B2 isoform X1
276 - - 71.4
18
Rho GTPase activating protein 44
254 - - 82.2
21
Endophilin-A2 isoform 1
237
3D
 1zwwB00 - 81.9
19
rho GTPase-activating protein 17 isoform X1
236 - - 79.0
20
SLIT-ROBO Rho GTPase activating protein 3
230 - - 56.9
22
Sorting nexin 3 protein
228 - - 97.5
23
Interacting with PRKCA
222 - - 86.0
24
growth arrest-specific protein 7 isoform X2
220 - - 62.9
25
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2
215 - - 96.5
26
FCH and double SH3 domains protein 2
206 - - 78.4
27
dynamin-binding protein isoform X1
185 - - 67.6
28
Bridging integrator 3 homolog
152 - - 91.6
29
Tyrosine-protein kinase
140 - - 90.5
31
Putative DCC-interacting protein 13-beta isoform 2
137
3D
 5c5bD01 - 82.6
32
Sorting nexin
135
3D
 3dytA02 - 37.9
30
Tyrosine-protein kinase
133
3D
 4dylA01 - 84.5
34
DCC-interacting protein 13-alpha isoform X2
130
3D
 5c5bC01 - 85.1
33
Sorting nexin
128
3D
 4akvB02 - 88.2
35
Sorting nexin 4
111 - - 38.1
36
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
106 - - 94.3
37
Proline-serine-threonine phosphatase interacting protein 1
103 - - 91.9
38
Rho GTPase activating protein 29
102 - - 38.0
39
FCH and double SH3 domains protein
99 - - 82.0
40
GEM-interacting protein isoform X1
99
3D
 3qweA00 - 41.7
41
F-BAR and double SH3 domains protein 1
97 - - 78.5
42
Vacuolar targeting protein Atg24
95 - - 94.8
43
Brain-specific angiogenesis inhibitor 1-associated protein 2-like 1
94 - - 91.4
44
Sorting nexin 1
84 - - 71.8
45
Cell division control protein
81 - - 92.5
46
Vacuolar protein sorting-associated protein 17
81 - - 88.3
47
protein FAM92A isoform X1
75 - - 66.5
48
BAR adaptor protein RVS167
74 - - 91.7
49
Sorting nexin 8
72 - - 47.1
52
Rho GTPase activating protein 4
69 - - 63.9
50
RhoGAP and Fes/CIP4 domain protein
69 - - 71.8
51
ARF GTPase activator
Csx2
69 - - 86.2
53
SH3 domain-binding protein 1
68 - - 93.9
54
Proline-serine-threonine phosphatase interacting protein 2
67 - - 75.7
56
brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2
66
3D
 3ok8B00 - 70.2
55
Uncharacterized protein, isoform F
66 - - 18.8
59
Rho GTPase activating protein 4b
58 - - 81.6
58
Rho GTPase activating protein 45
58 - - 25.3
57
Rho guanine nucleotide exchange factor 37
58 - - 79.6
60
Actin polymerization protein Bzz1
55 - - 98.8
61
Rho guanine nucleotide exchange factor 38
52 - - 83.2
62
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
49
3D
 4nswB01 - 61.0
63
Rho GTPase activator
45
3D
 4wpcB00 - 95.7
64
Tyrosine-protein kinase
38 - - 39.0
66
Metastasis suppressor protein 1
38 - - 25.5
65
Uncharacterized protein, isoform B
38 - - 25.1
68
Islet cell autoantigen
37 - - 84.5
67
NOSTRIN isoform 1
37 - - 33.6
69
Nostrin, isoform D
36 - - 29.2
70
Uncharacterized protein, isoform C
33 - - 38.4
71
Uncharacterized protein, isoform U
32 - - 66.4
72
Sorting nexin MVP1
30 - - 80.4
74
Rho GTPase-activating protein 42
27 - - 84.0
73
RhoGAP and Fes/CIP4 domain protein
27 - - 57.9
75
Related to IVY1-phospholipid-binding protein
26 - - 86.1
76
Rho GTPase activating protein 42
25 - - 31.6
77
SH3 domain-containing protein 1
24 - - 50.6
78
Slm1p
24 - - 84.3
79
Transcription factor SipA3
24 - - 71.8
80
ADP-ribosylation factor GTPase-activating protein AGD3
23 - - 39.3
81
Sorting nexin 2B
23 - - 60.2
205
Protein kinase C and casein kinase substrate in neurons protein 1
23
3D
 3qniB01 - 42.1
82
Endophilin B, isoform C
21 - - 16.8
83
Rho guanyl nucleotide exchange factor, putative
20 - - 77.6
84
BAI1-associated protein 2-like 2b
20 - - 47.4
85
Predicted protein
19 - - 97.1
86
Rho GTPase-activating protein 10
18 - - 65.2
87
Rho guanyl nucleotide exchange factor
17 - - 19.3
88
Ivy1p
15 - - 39.3
89
BAI1 associated protein 2
15 - - 31.7
90
Snx4p
15 - - 29.7
91
Sorting nexin 1
15 - - 74.4
92
Gvp36p
14 - - 11.5
94
SLIT-ROBO Rho GTPase-activating 2 protein
14 - - 95.3
93
Rho GTPase-activating protein 92B
14 - - 18.4
95
Hydroxyproline-rich glycoprotein family protein
13 - - 43.7
96
Unplaced genomic scaffold supercont2.2, whole genome shotgun sequence
13 - - 71.5
97
Vacuolar protein sorting-associated protein 17
13 - - 43.2
101
F-BAR and double SH3 domains protein 2 isoform X6
12 - - 86.6
99
Rho guanine nucleotide exchange factor 37
12 - - 87.4
100
Unplaced genomic scaffold supercont2.8, whole genome shotgun sequence
12 - - 40.8
102
WGS project CABT00000000 data, contig 2.23
12 - - 91.9
98
FCH and double SH3 domains protein 2 isoform X3
12 - - 23.2
104
Unplaced genomic scaffold supercont1.20, whole genome shotgun sequence
11 - - 9.3
105
Ysp1p
11 - - 9.4
107
Slit-Robo GAP homolog
11 - - 41.5
103
Hof1p
11 - - 17.2
106
Atg20p
11 - - 12.9
114
Formin-binding protein 1-like
10 - - 37.8
113
Atg20p
10 - - 3.1
111
YPR148C-like protein
10 - - 11.9
109
Rho-GTPase-activating protein RGD2
10 - - 10.4
110
Sorting nexin
10 - - 10.7
108
Rho-GTPase-activating protein RGD2
10 - - 41.6
112
YKR078W-like protein
10 - - 3.1
116
Suppressor of yeast profilin deletion
10
3D
 3g9gA00 - 0.8
115
Putative Dynamin-binding protein
9 - - 10.4
117
SynDaPiN
Synaptic dynamin binding protein
9 - - 29.8
120
YPR115W-like protein
9 - - 2.0
119
Unplaced genomic scaffold supercont1.126, whole genome shotgun sequence
9 - - 7.9
121
GTPase activating protein, putative
9 - - 79.7
118
Unplaced genomic scaffold supercont1.83, whole genome shotgun sequence
9 - - 12.5
126
SIP3p Transcription cofactor
8 - - 0.0
122
Protein CBG22463
8 - - 21.1
123
Related to SYP1/YCR030C
8 - - 22.0
125
Putative phosphoinositide-binding protein
8 - - 10.8
124
Endophilin-A homolog
8 - - 11.7
134
Glucosamine 6-phosphate N-acetyltransferase, putative
7 - - 79.1
128
FCH domain Only
FCH stands for Fes/CIP4 homology domain
7 - - 25.6
131
Variant sh3 domain containing protein
7 - - 3.0
133
SLIT-ROBO Rho GTPase-activating protein 2
7 - - 36.0
132
Rho GTPase Activating protein
7 - - 0.0
130
Variant sh3 domain containing protein
7 - - 4.3
129
Islet cell autoantigen
7 - - 2.1
167
Bridging integrator 2
7
3D
 4i1qB00 - 35.3
127
Protein CBG03954
7 - - 26.8
137
Uncharacterized protein
6 - - 14.7
143
Proline-serine-threonine phosphatase-interacting protein 1b
6 - - 35.7
135
GTPase activating protein, putative
6 - - 11.5
141
WGS project CABT00000000 data, contig 2.6
6 - - 7.8
139
Uncharacterized protein
6 - - 5.4
138
Chromosome 9, whole genome shotgun sequence
6 - - 16.2
136
Uncharacterized protein
6 - - 13.3
142
Rho GTPase-activating protein 92B
6 - - 7.4
140
Variant sh3 domain containing protein
6 - - 0.5
149
GH04442p
5 - - 11.1
156
SLIT-ROBO Rho GTPase-activating protein 2 isoform X8
5 - - 30.1
150
Arp2/3 complex-activating protein ricka, putative
5 - - 0.6
147
Protein CBG09025
5 - - 11.1
152
Formin 2,3 and collagen domain containing protein
5 - - 3.3
144
Uncharacterized protein
5 - - 68.5
145
Uncharacterized protein
5 - - 0.0
153
Uncharacterized protein
5 - - 14.8
151
Uncharacterized protein
5 - - 0.4
146
Glucosamine 6-phosphate N-acetyltransferase
5 - - 5.7
155
Uncharacterized protein
5 - - 13.8
148
Unplaced genomic scaffold supercont1.21, whole genome shotgun sequence
5 - - 11.0
154
Sorting nexin-2
5 - - 3.1
166
Sorting NeXin
4 - - 65.8
168
Sorting nexin 7
4 - - 7.7
162
Rho GTPase-activating protein 17
4 - - 76.6
160
ADP-ribosylation factor-interacting protein 2a
4 - - 47.9
158
Bridging integrator 2
4 - - 12.8
163
AGAP009727-PA
4 - - 13.9
161
Hypothetical_protein_-_conserved
4 - - 7.0
159
Zgc:158689
4 - - 19.5
164
Putative Sip3 protein
4 - - 0.5
165
BAI1-associated protein 2
4 - - 62.2
157
Uncharacterized protein
4 - - 12.5
171
Rho GTPase-activating protein 10
3 - - 4.4
173
Uncharacterized protein
3 - - 9.8
185
Uncharacterized protein
3 - - 12.3
184
Uncharacterized protein
3 - - 12.3
179
sorting nexin-6
3 - - 0.0
174
Meiotically up-regulated gene 137 protein
3 - - 79.5
181
Vacuolar protein sorting-associated protein 17
3 - - 5.0
175
SH3 domain signalling protein
AFU_orthologue AFUA_5G07670
3 - - 8.1
183
Sorting nexin, putative
3 - - 9.9
177
Uncharacterized protein
3 - - 7.5
169
Rgd3p
3 - - 4.4
180
Vacuolar protein sorting-associated protein 17
3 - - 0.0
182
Autophagy-related protein 24
3 - - 0.0
176
Uncharacterized protein
3 - - 2.5
170
Rgd3p
3 - - 1.6
186
Transcription modulator, putative
3 - - 6.1
178
Cell division control protein, putative
3 - - 1.3
172
Protein kinase C and casein kinase substrate in neurons 3
3 - - 30.3
228
Protein kinase C and casein kinase substrate in neurons protein 1
2 - - 0.4
192
YALI0D07524p
2 - - 0.0
245
Uncharacterized protein
2 - - 45.9
231
Uncharacterized protein
2 - - 0.0
233
Uncharacterized protein
2 - - 16.6
209
Bridging integrator 3-like protein
2 - - 0.0
198
YALI0B15686p
2 - - 0.0
222
Uncharacterized protein
2 - - 17.1
219
Uncharacterized protein
2 - - 9.9
244
Rho-GTPase-activating protein 8
2 - - 38.6
239
Uncharacterized protein
2 - - 2.0
190
Uncharacterized protein
2 - - 39.3
201
growth arrest-specific protein 7
2 - - 0.0
213
Chromosome 13 SCAF14555, whole genome shotgun sequence
2 - - 8.9
211
Bridging integrator 1b
2 - - 6.3
247
Rho GTPase-activating protein 4
2 - - 21.0
203
rho GTPase-activating protein 26
2 - - 0.0
187
YALI0E05489p
2 - - 2.4
220
SH3 and F-BAR domain-containing protein DDB_G0274695
2 - - 19.3
196
AaceriAFR725Cp
2 - - 4.3
234
YALI0E13904p
2 - - 0.0
243
Islet cell autoantigen, putative
2 - - 37.6
207
YALI0F01694p
2 - - 0.0
217
Uncharacterized protein
2 - - 0.4
241
Nitric oxide synthase-trafficking
2 - - 0.5
235
Uncharacterized protein
2 - - 6.6
226
Brain-specific angiogenesis inhibitor 1-associated protein 2
2 - - 2.6
215
Uncharacterized protein
2 - - 0.0
237
Mental retardation GTPase activating protein homolog 4
2 - - 20.0
189
Dip13 beta, putative
2 - - 45.4
214
GRAF
2 - - 6.9
204
Uncharacterized protein
2 - - 13.3
240
rho GTPase-activating protein 17 isoform X1
2 - - 0.0
227
Uncharacterized protein
2 - - 0.0
216
Fcho-1
2 - - 3.0
206
Uncharacterized protein
2 - - 5.5
197
YALI0B15686p
2 - - 0.0
224
Uncharacterized protein
2 - - 0.0
195
Age1p
2 - - 0.6
242
Uncharacterized protein
2 - - 0.0
188
Uncharacterized protein
2 - - 20.9
236
Rho GTPase-activating protein gacP
2 - - 15.6
194
Dynamin-binding protein
2 - - 0.0
225
YALI0F19778p
2 - - 0.0
229
Sdpn-1
2 - - 0.0
212
Uncharacterized protein
2 - - 0.0
202
Uncharacterized protein
2 - - 1.5
199
Uncharacterized protein
2 - - 0.0
208
YALI0C03245p
2 - - 0.0
230
AaceriABR082Wp
2 - - 4.6
218
AEL147Wp
2 - - 6.8
238
Uncharacterized protein
2 - - 39.8
210
arfaptin-2-like isoform X2
2 - - 1.0
200
Uncharacterized protein
2 - - 0.0
246
Uncharacterized protein
2 - - 39.6
221
SH3 domain-containing protein
2 - - 12.6
223
F-BAR and double SH3 domains protein 2
2 - - 0.4
232
Uncharacterized protein
2 - - 0.5
191
Uncharacterized protein
2 - - 0.0
193
YALI0F13673p
2 - - 0.0
339
AFR651Wp
1 - - 0.0
289
Uncharacterized protein
1 - - 0.0
260
Uncharacterized protein
1 - - 0.0
258
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
1 - - 0.0
277
Uncharacterized protein
1 - - 0.0
320
AGAP001369-PA
1 - - 0.0
313
BAI1-associated protein 2b
1 - - 0.0
252
Uncharacterized protein
1 - - 0.0
301
Uncharacterized protein
1 - - 0.0
303
Uncharacterized protein
1 - - 0.0
311
Uncharacterized protein
1 - - 0.0
331
Uncharacterized protein
1 - - 0.0
262
Predicted protein
1 - - 0.0
333
Uncharacterized protein
1 - - 0.0
328
Uncharacterized protein
1 - - 0.0
281
Uncharacterized protein
1 - - 0.0
283
Uncharacterized protein
1 - - 0.0
275
Uncharacterized protein
1 - - 0.0
250
Uncharacterized protein
1 - - 0.0
268
Zgc:158689
1 - - 0.0
296
Uncharacterized protein
1 - - 0.0
309
Uncharacterized protein
1 - - 0.0
322
Uncharacterized protein
1 - - 0.0
274
Uncharacterized protein
1 - - 0.0
319
Bridging integrator, putative
1 - - 0.0
337
Uncharacterized protein
1 - - 0.0
315
Uncharacterized protein
1 - - 0.0
305
Uncharacterized protein
1 - - 0.0
287
Uncharacterized protein
1 - - 0.0
279
Uncharacterized protein
1 - - 0.0
314
Uncharacterized protein
1 - - 0.0
304
Uncharacterized protein
1 - - 0.0
256
Rho-GTPase-activating protein 8
1 - - 0.0
290
Protein kinase C and casein kinase substrate in neurons 1a
1 - - 0.0
266
Uncharacterized protein
1 - - 0.0
298
Uncharacterized protein
1 - - 0.0
284
Predicted protein
1 - - 0.0
334
Rho GTPase-activating protein 44
1 - - 0.0
271
Uncharacterized protein
1 - - 0.0
292
Bridging integrator 2b
1 - - 0.0
285
Uncharacterized protein
1 - - 0.0
249
Probable Rho-GTPase-activating protein 9
1 - - 0.0
273
Zgc:158689
1 - - 0.0
343
Uncharacterized protein
1 - - 0.0
307
Uncharacterized protein
1 - - 0.0
341
Uncharacterized protein
1 - - 0.0
326
SH3-domain GRB2-like 3b
1 - - 0.0
335
Uncharacterized protein
1 - - 0.0
317
Variant SH3 domain containing protein
1 - - 0.0
265
Uncharacterized protein
1 - - 0.0
342
Uncharacterized protein
1 - - 0.0
257
BAR domaincontaining protein
1 - - 0.0
291
Predicted protein
1 - - 0.0
324
Uncharacterized protein
1 - - 0.0
272
Protein kinase C alpha binding protein, putative
1 - - 0.0
293
Uncharacterized protein
1 - - 0.0
264
Uncharacterized protein
1 - - 0.0
286
Uncharacterized protein
1 - - 0.0
278
Uncharacterized protein
1 - - 0.0
325
Predicted protein
1 - - 0.0
336
Uncharacterized protein
1 - - 0.0
316
DDEFL1 protein
1 - - 0.0
327
Uncharacterized protein
1 - - 0.0
306
Meiotically up-regulated gene 64 protein
1 - - 0.0
270
Uncharacterized protein
1 - - 0.0
254
Inositol-pentakisphosphate 2-kinase
1 - - 0.0
299
Uncharacterized protein
1 - - 0.0
340
Uncharacterized PH domain-containing protein C19A8.02
1 - - 0.0
255
Uncharacterized protein
1 - - 0.0
267
LD28528p
1 - - 0.0
248
Chromosome 16, whole genome shotgun sequence
1 - - 0.0
288
FES proto-oncogene, tyrosine kinase
1 - - 0.0
321
Ubp4-interactor sfp47
1 - - 0.0
323
Insulin receptor tyrosine kinase substrate, putative
1 - - 0.0
294
Asap2a protein
1 - - 0.0
259
Uncharacterized protein
1 - - 0.0
310
Uncharacterized protein
1 - - 0.0
338
Uncharacterized protein
1 - - 0.0
300
Uncharacterized protein
1 - - 0.0
276
Dip13 beta, putative
1 - - 0.0
295
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
1 - - 0.0
282
Uncharacterized protein
1 - - 0.0
263
Rho GTPase-activating protein 26-like Protein
1 - - 0.0
332
Predicted protein
1 - - 0.0
261
Predicted protein
1 - - 0.0
253
Chromosome 19, whole genome shotgun sequence
1 - - 0.0
329
Sorting nexin-41
1 - - 0.0
312
Uncharacterized protein
1 - - 0.0
251
Chromosome 1, whole genome shotgun sequence
1 - - 0.0
302
Uncharacterized protein
1 - - 0.0
297
Uncharacterized protein
1 - - 0.0
308
Uncharacterized protein
1 - - 0.0
318
Uncharacterized protein
1 - - 0.0
330
Uncharacterized protein
1 - - 0.0
269
Uncharacterized protein
1 - - 0.0
280
Uncharacterized protein
1 - - 0.0
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