CATH Superfamily 1.20.1270.290
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 1: MLLT3, super elongation complex subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | A2AM29 (/IPI) A4VCJ2 (/IPI) P42568 (/IPI) P42568 (/IPI) P42568 (/IPI) P42568 (/IPI) P42568 (/IPI) Q03111 (/IPI) Q9EPX7 (/IPI) Q9ERL0 (/IPI) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | P42568 (/ISM) P42568 (/ISM) P42568 (/ISM) P42568 (/ISM) P42568 (/ISM) Q03111 (/ISM) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
5 | P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) |
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
5 | P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) |
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
5 | P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) |
Modification-dependent protein binding GO:0140030
Interacting selectively and non-covalently with a protein upon post-translation modification of the target protein.
|
5 | P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q03111 (/TAS) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | A2AM29 (/ISO) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | A2AM29 (/ISS) |
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | A2AM29 (/ISO) |
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | A2AM29 (/ISS) |
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
1 | A2AM29 (/ISO) |
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
1 | A2AM29 (/ISS) |
Modification-dependent protein binding GO:0140030
Interacting selectively and non-covalently with a protein upon post-translation modification of the target protein.
|
1 | A2AM29 (/ISO) |
Modification-dependent protein binding GO:0140030
Interacting selectively and non-covalently with a protein upon post-translation modification of the target protein.
|
1 | A2AM29 (/ISS) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
6 | P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) Q03111 (/TAS) |
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
|
6 | P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) Q03111 (/TAS) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) |
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
5 | P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) |
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
5 | P42568 (/IGI) P42568 (/IGI) P42568 (/IGI) P42568 (/IGI) P42568 (/IGI) |
Positive regulation of Wnt signaling pathway, planar cell polarity pathway GO:2000096
Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.
|
5 | P42568 (/IGI) P42568 (/IGI) P42568 (/IGI) P42568 (/IGI) P42568 (/IGI) |
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
|
3 | A4VCJ2 (/IDA) Q9EPX7 (/IDA) Q9ERL0 (/IDA) |
Segment specification GO:0007379
The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.
|
1 | A2AM29 (/IMP) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | A2AM29 (/IMP) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | A2AM29 (/ISO) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | A2AM29 (/ISS) |
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | A2AM29 (/ISO) |
Positive regulation of Wnt signaling pathway, planar cell polarity pathway GO:2000096
Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.
|
1 | A2AM29 (/ISO) |
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) Q03111 (/TAS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) P42568 (/TAS) Q03111 (/TAS) |
Transcription elongation factor complex GO:0008023
Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.
|
6 | P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) P42568 (/IDA) Q03111 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
5 | P42568 (/HDA) P42568 (/HDA) P42568 (/HDA) P42568 (/HDA) P42568 (/HDA) |
Transcription elongation factor complex GO:0008023
Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.
|
4 | A2AM29 (/ISO) A4VCJ2 (/ISO) Q9EPX7 (/ISO) Q9ERL0 (/ISO) |
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
|
3 | A4VCJ2 (/ISO) Q9EPX7 (/ISO) Q9ERL0 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | A4VCJ2 (/IDA) Q9EPX7 (/IDA) Q9ERL0 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | A4VCJ2 (/ISO) Q9EPX7 (/ISO) Q9ERL0 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | A4VCJ2 (/ISO) Q9EPX7 (/ISO) Q9ERL0 (/ISO) |
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
|
1 | Q03111 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q03111 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q03111 (/IDA) |
Transcription elongation factor complex GO:0008023
Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.
|
1 | A2AM29 (/ISS) |