The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Interleukin-34
".
FunFam 1: Interleukin-34
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Macrophage colony-stimulating factor receptor binding GO:0005157
Interacting selectively and non-covalently with the macrophage colony-stimulating factor receptor.
|
3 | A6QL48 (/ISS) Q4KM46 (/ISS) Q8R1R4 (/ISS) |
|
Macrophage colony-stimulating factor receptor binding GO:0005157
Interacting selectively and non-covalently with the macrophage colony-stimulating factor receptor.
|
2 | Q6ZMJ4 (/IDA) Q6ZMJ4 (/IDA) |
|
Macrophage colony-stimulating factor receptor binding GO:0005157
Interacting selectively and non-covalently with the macrophage colony-stimulating factor receptor.
|
1 | Q8R1R4 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q8R1R4 (/ISO) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
|
4 | A6QL48 (/ISS) Q4KM46 (/ISS) Q6ZMJ4 (/ISS) Q6ZMJ4 (/ISS) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
3 | A6QL48 (/ISS) Q4KM46 (/ISS) Q8R1R4 (/ISS) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
3 | A6QL48 (/ISS) Q4KM46 (/ISS) Q8R1R4 (/ISS) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
2 | Q6ZMJ4 (/IDA) Q6ZMJ4 (/IDA) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | Q6ZMJ4 (/IDA) Q6ZMJ4 (/IDA) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q6ZMJ4 (/TAS) Q6ZMJ4 (/TAS) |
|
Positive regulation of macrophage differentiation GO:0045651
Any process that activates or increases the frequency, rate or extent of macrophage differentiation.
|
2 | Q6ZMJ4 (/IDA) Q6ZMJ4 (/IDA) |
|
Positive regulation of monocyte differentiation GO:0045657
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
2 | Q6ZMJ4 (/IDA) Q6ZMJ4 (/IDA) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
1 | Q8R1R4 (/ISO) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q8R1R4 (/ISO) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q8R1R4 (/IDA) |
|
Positive regulation of macrophage differentiation GO:0045651
Any process that activates or increases the frequency, rate or extent of macrophage differentiation.
|
1 | Q8R1R4 (/ISO) |
|
Positive regulation of monocyte differentiation GO:0045657
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
1 | Q8R1R4 (/ISO) |
|
Positive regulation of oligodendrocyte differentiation GO:0048714
Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
|
1 | Q8R1R4 (/IDA) |
|
Microglial cell proliferation GO:0061518
The expansion of a microglial cell population by cell division.
|
1 | Q8R1R4 (/IGI) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | A6QL48 (/ISS) Q4KM46 (/ISS) Q8R1R4 (/ISS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q6ZMJ4 (/TAS) Q6ZMJ4 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | Q6ZMJ4 (/IDA) Q6ZMJ4 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q8R1R4 (/ISO) |