The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Sec23/Sec24 helical domain
".
FunFam 4: SEC24 homolog B, COPII coat complex component
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | O95486 (/IPI) O95487 (/IPI) Q3UDH4 (/IPI) Q80ZX0 (/IPI) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
3 | Q3U2P1 (/ISO) Q3UDH4 (/ISO) Q80ZX0 (/ISO) |
|
Signal sequence binding GO:0005048
Interacting selectively and non-covalently with a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized.
|
2 | A0A0B4LEK8 (/ISS) A1Z813 (/ISS) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | O95486 (/IDA) O95487 (/IDA) |
There are 30 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
4 | A0A0B4LEK8 (/ISS) A1Z813 (/ISS) A6QNT8 (/ISS) Q3U2P1 (/ISS) |
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
3 | Q3U2P1 (/ISO) Q3UDH4 (/ISO) Q80ZX0 (/ISO) |
|
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
3 | Q3U2P1 (/ISO) Q3UDH4 (/ISO) Q80ZX0 (/ISO) |
|
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
|
2 | Q3UDH4 (/IGI) Q80ZX0 (/IGI) |
|
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Auditory receptor cell morphogenesis GO:0002093
Any process that alters the size or shape of an auditory receptor cell.
|
2 | Q3UDH4 (/IGI) Q80ZX0 (/IGI) |
|
Auditory receptor cell morphogenesis GO:0002093
Any process that alters the size or shape of an auditory receptor cell.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Antigen processing and presentation of peptide antigen via MHC class I GO:0002474
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
|
2 | O95486 (/TAS) O95487 (/TAS) |
|
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
2 | O95486 (/IMP) O95487 (/IMP) |
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
2 | A6QNT8 (/ISS) Q3U2P1 (/ISS) |
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
2 | O95486 (/TAS) O95487 (/TAS) |
|
Antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
|
2 | O95486 (/TAS) O95487 (/TAS) |
|
Cochlear nucleus development GO:0021747
The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.
|
2 | Q3UDH4 (/IGI) Q80ZX0 (/IGI) |
|
Cochlear nucleus development GO:0021747
The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Aorta morphogenesis GO:0035909
The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
2 | O95486 (/TAS) O95487 (/TAS) |
|
Auditory receptor cell stereocilium organization GO:0060088
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
|
2 | Q3UDH4 (/IGI) Q80ZX0 (/IGI) |
|
Auditory receptor cell stereocilium organization GO:0060088
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Lung morphogenesis GO:0060425
The process in which the anatomical structures of the lung are generated and organized.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Lung lobe morphogenesis GO:0060463
The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Coronary artery morphogenesis GO:0060982
The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Pulmonary artery morphogenesis GO:0061156
The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Cardiovascular system development GO:0072358
The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
2 | O95486 (/IDA) O95487 (/IDA) |
|
Regulation of establishment of planar polarity involved in neural tube closure GO:0090178
Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Regulation of cargo loading into COPII-coated vesicle GO:1901301
Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle.
|
2 | Q3UDH4 (/IMP) Q80ZX0 (/IMP) |
|
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
|
1 | Q3U2P1 (/IMP) |
|
Regulation of low-density lipoprotein particle receptor biosynthetic process GO:0045714
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.
|
1 | Q3U2P1 (/IMP) |
|
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
|
1 | Q3U2P1 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
4 | O95486 (/IDA) O95487 (/IDA) Q3UDH4 (/IDA) Q80ZX0 (/IDA) |
|
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
4 | A0A0B4LEK8 (/ISS) A1Z813 (/ISS) A6QNT8 (/ISS) Q3U2P1 (/ISS) |
|
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
3 | Q3U2P1 (/ISO) Q3UDH4 (/ISO) Q80ZX0 (/ISO) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | O95486 (/TAS) O95487 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q3UDH4 (/ISO) Q80ZX0 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O95486 (/TAS) O95487 (/TAS) |
|
ER to Golgi transport vesicle membrane GO:0012507
The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
|
2 | O95486 (/TAS) O95487 (/TAS) |
|
COPII-coated ER to Golgi transport vesicle GO:0030134
A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
|
2 | Q3UDH4 (/ISO) Q80ZX0 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O95487 (/IDA) |
|
COPII-coated ER to Golgi transport vesicle GO:0030134
A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
|
1 | D3ZW15 (/IDA) |
