The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Sec23/Sec24 helical domain
".
FunFam 1: Protein transport protein SEC23
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
14 |
P15303 (/IPI)
P15303 (/IPI)
P15303 (/IPI)
P15303 (/IPI)
P15303 (/IPI)
P15303 (/IPI)
P15303 (/IPI)
P15303 (/IPI)
P15303 (/IPI)
Q15437 (/IPI)
(4 more) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
9 | P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
5 | A0A0B4K5Z8 (/ISS) A0A0B4K6T4 (/ISS) Q8IGT0 (/ISS) Q9NFN9 (/ISS) Q9VNF8 (/ISS) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | O74873 (/ISO) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | O74873 (/ISM) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q5ZK03 (/ISS) |
There are 28 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of COPII vesicle coating GO:0003400
Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
9 | P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) |
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
|
9 | P15303 (/IMP) P15303 (/IMP) P15303 (/IMP) P15303 (/IMP) P15303 (/IMP) P15303 (/IMP) P15303 (/IMP) P15303 (/IMP) P15303 (/IMP) |
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
9 | P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) |
Positive regulation of extracellular matrix constituent secretion GO:0003331
Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Regulation of COPII vesicle coating GO:0003400
Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
5 | A0A0B4K5Z8 (/ISS) A0A0B4K6T4 (/ISS) Q8IGT0 (/ISS) Q9NFN9 (/ISS) Q9VNF8 (/ISS) |
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
|
5 | A0A0B4K5Z8 (/IGI) A0A0B4K6T4 (/IGI) Q8IGT0 (/IGI) Q9NFN9 (/IGI) Q9VNF8 (/IGI) |
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Larval chitin-based cuticle development GO:0008363
Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Positive regulation of cell-cell adhesion GO:0022409
Any process that activates or increases the rate or extent of cell adhesion to another cell.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Maintenance of cell polarity GO:0030011
The maintenance of established anisotropic intracellular organization or cell growth patterns.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Protein localization to cell surface GO:0034394
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Lumen formation, open tracheal system GO:0035149
Creation of the central hole of a tube in an open tracheal system through which gases flow.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Chitin-based larval cuticle pattern formation GO:0035293
The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Chitin-based cuticle development GO:0040003
Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
5 | A0A0B4K5Z8 (/ISS) A0A0B4K6T4 (/ISS) Q8IGT0 (/ISS) Q9NFN9 (/ISS) Q9VNF8 (/ISS) |
Positive regulation of cuticle pigmentation GO:0048081
Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Positive regulation of dendrite morphogenesis GO:0050775
Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
5 | A0A0B4K5Z8 (/IMP) A0A0B4K6T4 (/IMP) Q8IGT0 (/IMP) Q9NFN9 (/IMP) Q9VNF8 (/IMP) |
Embryonic neurocranium morphogenesis GO:0048702
The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.
|
4 | F1R7W8 (/IMP) Q6AZ98 (/IMP) Q6TNV9 (/IMP) Q7ZVV7 (/IMP) |
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
|
4 | F1R7W8 (/IMP) Q6AZ98 (/IMP) Q6TNV9 (/IMP) Q7ZVV7 (/IMP) |
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
4 | F1R7W8 (/IMP) Q6AZ98 (/IMP) Q6TNV9 (/IMP) Q7ZVV7 (/IMP) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | O74873 (/IC) |
Ubiquitin-dependent ERAD pathway GO:0030433
The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
|
1 | O74873 (/ISO) |
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
1 | Q5ZK03 (/ISS) |
There are 18 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
9 | P15303 (/HDA) P15303 (/HDA) P15303 (/HDA) P15303 (/HDA) P15303 (/HDA) P15303 (/HDA) P15303 (/HDA) P15303 (/HDA) P15303 (/HDA) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
9 | P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) P15303 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
8 | A0A0B4K5Z8 (/IDA) A0A0B4K6T4 (/IDA) Q15437 (/IDA) Q15437 (/IDA) Q15437 (/IDA) Q8IGT0 (/IDA) Q9NFN9 (/IDA) Q9VNF8 (/IDA) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
6 | A0A0B4K5Z8 (/ISS) A0A0B4K6T4 (/ISS) Q5ZK03 (/ISS) Q8IGT0 (/ISS) Q9NFN9 (/ISS) Q9VNF8 (/ISS) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
5 | Q3SZN2 (/ISS) Q3SZN2 (/ISS) Q5R5G2 (/ISS) Q9D662 (/ISS) Q9D662 (/ISS) |
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
|
5 | A0A0B4K5Z8 (/IDA) A0A0B4K6T4 (/IDA) Q8IGT0 (/IDA) Q9NFN9 (/IDA) Q9VNF8 (/IDA) |
COPII-coated ER to Golgi transport vesicle GO:0030134
A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
|
5 | A0A0B4K5Z8 (/TAS) A0A0B4K6T4 (/TAS) Q8IGT0 (/TAS) Q9NFN9 (/TAS) Q9VNF8 (/TAS) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
5 | A0A0B4K5Z8 (/IDA) A0A0B4K6T4 (/IDA) Q8IGT0 (/IDA) Q9NFN9 (/IDA) Q9VNF8 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | F4JUM1 (/IDA) Q8H0S3 (/IDA) Q8H0S3 (/IDA) |
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
|
3 | Q15437 (/IDA) Q15437 (/IDA) Q15437 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | Q9D662 (/ISO) Q9D662 (/ISO) |
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
|
2 | Q9D662 (/ISO) Q9D662 (/ISO) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | Q9D662 (/IDA) Q9D662 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q5BGR9 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q5ZK03 (/ISS) |
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
1 | Q5ZK03 (/ISS) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
1 | O74873 (/ISO) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
1 | Q5ZK03 (/ISS) |