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CATH Superfamily 1.20.1080.10

Glycerol uptake facilitator protein.

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glycerol uptake facilitator protein.
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 32: Aquaporin-2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Water channel activity GO:0015250
Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
 15 O77697 (/ISS) O77697 (/ISS) O77697 (/ISS) O77714 (/ISS) O77714 (/ISS) O77722 (/ISS) O77740 (/ISS) P79144 (/ISS) P79164 (/ISS) P79165 (/ISS)
(5 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Water transport GO:0006833
The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 15 O77697 (/ISS) O77697 (/ISS) O77697 (/ISS) O77714 (/ISS) O77714 (/ISS) O77722 (/ISS) O77740 (/ISS) P79144 (/ISS) P79164 (/ISS) P79165 (/ISS)
(5 more)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
 15 O77697 (/ISS) O77697 (/ISS) O77697 (/ISS) O77714 (/ISS) O77714 (/ISS) O77722 (/ISS) O77740 (/ISS) P79144 (/ISS) P79164 (/ISS) P79165 (/ISS)
(5 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 15 O77697 (/ISS) O77697 (/ISS) O77697 (/ISS) O77714 (/ISS) O77714 (/ISS) O77722 (/ISS) O77740 (/ISS) P79144 (/ISS) P79164 (/ISS) P79165 (/ISS)
(5 more)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
 15 O77697 (/ISS) O77697 (/ISS) O77697 (/ISS) O77714 (/ISS) O77714 (/ISS) O77722 (/ISS) O77740 (/ISS) P79144 (/ISS) P79164 (/ISS) P79165 (/ISS)
(5 more)