The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Rhodopsin 7-helix transmembrane proteins
".
FunFam 546: DOPamine receptor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Dopamine neurotransmitter receptor activity, coupled via Gs GO:0001588
Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.
|
3 | Q86ME4 (/IDA) Q86ME5 (/IDA) Q86ME6 (/IDA) |
|
Epinephrine binding GO:0051379
Interacting selectively and non-covalently with epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
|
3 | Q86ME4 (/IDA) Q86ME5 (/IDA) Q86ME6 (/IDA) |
|
Norepinephrine binding GO:0051380
Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
|
3 | Q86ME4 (/IDA) Q86ME5 (/IDA) Q86ME6 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Adenylate cyclase-activating dopamine receptor signaling pathway GO:0007191
The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
|
3 | Q86ME4 (/IDA) Q86ME5 (/IDA) Q86ME6 (/IDA) |
|
Dopamine receptor signaling pathway GO:0007212
The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
|
3 | Q86ME4 (/IGI) Q86ME5 (/IGI) Q86ME6 (/IGI) |
|
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
|
3 | Q86ME4 (/IMP) Q86ME5 (/IMP) Q86ME6 (/IMP) |
|
Response to food GO:0032094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
|
3 | Q86ME4 (/IGI) Q86ME5 (/IGI) Q86ME6 (/IGI) |
|
Regulation of locomotion GO:0040012
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
|
3 | Q86ME4 (/IGI) Q86ME5 (/IGI) Q86ME6 (/IGI) |
|
Habituation GO:0046959
A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.
|
3 | Q86ME4 (/IMP) Q86ME5 (/IMP) Q86ME6 (/IMP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
