The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Rhodopsin 7-helix transmembrane proteins
".
FunFam 34: G-protein coupled receptor 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 39 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Complement component C5a receptor activity GO:0004878
Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
12 |
O70129 (/ISS)
P0C7U5 (/ISS)
P30992 (/ISS)
P30993 (/ISS)
P79175 (/ISS)
P79188 (/ISS)
P79234 (/ISS)
P79240 (/ISS)
P79240 (/ISS)
Q6UNA4 (/ISS)
(2 more) |
|
N-formyl peptide receptor activity GO:0004982
Combining with an N-formyl peptide to initiate a change in cell activity.
|
7 | A4FUQ5 (/IDA) O88536 (/IDA) O88537 (/IDA) P21462 (/IDA) P33766 (/IDA) Q3SXG2 (/IDA) Q71MR7 (/IDA) |
|
N-formyl peptide receptor activity GO:0004982
Combining with an N-formyl peptide to initiate a change in cell activity.
|
5 | P21462 (/TAS) P25089 (/TAS) P25089 (/TAS) P25090 (/TAS) P25090 (/TAS) |
|
Complement component C5a binding GO:0001856
Interacting selectively and non-covalently with the C5a product of the complement cascade.
|
4 | A0A060YND6 (/IPI) A0A060YND6 (/IPI) Q6UNA4 (/IPI) Q6UNA4 (/IPI) |
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
4 | P25090 (/TAS) P25090 (/TAS) P46091 (/TAS) Q9Y5Y4 (/TAS) |
|
Scavenger receptor binding GO:0005124
Interacting selectively and non-covalently with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.
|
4 | D4A7Q2 (/IPI) F1M670 (/IPI) P25090 (/IPI) P25090 (/IPI) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
4 | O08790 (/IDA) O88536 (/IDA) P25090 (/IDA) P25090 (/IDA) |
|
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
3 | O88536 (/IPI) P25090 (/IPI) P25090 (/IPI) |
|
Complement component C5a receptor activity GO:0004878
Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
3 | P21730 (/IDA) P30993 (/IDA) P97520 (/IDA) |
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
3 | P25090 (/NAS) P25090 (/NAS) Q99788 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P21462 (/IPI) P46091 (/IPI) Q99788 (/IPI) |
|
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
Complement component C5a receptor activity GO:0004878
Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
2 | P21730 (/TAS) P97520 (/TAS) |
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
2 | Q9Y5Y4 (/IDA) Q9Z2J6 (/IDA) |
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
2 | P30993 (/ISO) Q9Z2J6 (/ISO) |
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
2 | Q6XKD3 (/ISS) Q9Z2J6 (/ISS) |
|
Prostaglandin D receptor activity GO:0004956
Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.
|
2 | Q9Y5Y4 (/IDA) Q9Z2J6 (/IDA) |
|
Scavenger receptor binding GO:0005124
Interacting selectively and non-covalently with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.
|
2 | O88536 (/ISO) P33766 (/ISO) |
|
Cargo receptor activity GO:0038024
Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
RAGE receptor binding GO:0050786
Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products.
|
2 | D4A7Q2 (/IPI) F1M670 (/IPI) |
|
RAGE receptor binding GO:0050786
Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products.
|
2 | O88536 (/ISO) P33766 (/ISO) |
|
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
1 | O88536 (/ISO) |
|
G protein-coupled chemoattractant receptor activity GO:0001637
Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
1 | O35786 (/TAS) |
|
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
1 | P21462 (/IDA) |
|
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
1 | P33766 (/ISO) |
|
Prostaglandin J receptor activity GO:0001785
Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.
|
1 | Q9Z2J6 (/IDA) |
|
Complement component C5a binding GO:0001856
Interacting selectively and non-covalently with the C5a product of the complement cascade.
|
1 | P97520 (/IDA) |
|
Complement component C5a binding GO:0001856
Interacting selectively and non-covalently with the C5a product of the complement cascade.
|
1 | P30993 (/ISO) |
|
Complement component C5a receptor activity GO:0004878
Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | P30993 (/ISO) |
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
1 | P21730 (/IPI) |
|
Chemokine receptor activity GO:0004950
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
1 | Q99788 (/TAS) |
|
Prostaglandin D receptor activity GO:0004956
Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.
|
1 | Q9Z2J6 (/ISO) |
|
Prostaglandin D receptor activity GO:0004956
Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.
|
1 | Q6XKD3 (/ISS) |
|
Prostaglandin F receptor activity GO:0004958
Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity.
|
1 | Q9Z2J6 (/IDA) |
|
N-formyl peptide receptor activity GO:0004982
Combining with an N-formyl peptide to initiate a change in cell activity.
|
1 | P33766 (/ISO) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
1 | O88536 (/ISO) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
1 | Q99788 (/TAS) |
|
Cargo receptor activity GO:0038024
Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.
|
1 | F1M670 (/IMP) |
|
Cargo receptor activity GO:0038024
Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.
|
1 | O88536 (/ISO) |
There are 129 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
15 |
O70129 (/ISS)
P0C7U5 (/ISS)
P25090 (/ISS)
P25090 (/ISS)
P30992 (/ISS)
P30993 (/ISS)
P79175 (/ISS)
P79188 (/ISS)
P79234 (/ISS)
P79240 (/ISS)
(5 more) |
|
MRNA transcription by RNA polymerase II GO:0042789
The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
|
13 |
O70129 (/ISS)
P0C7U5 (/ISS)
P30992 (/ISS)
P30993 (/ISS)
P79175 (/ISS)
P79188 (/ISS)
P79234 (/ISS)
P79240 (/ISS)
P79240 (/ISS)
P97520 (/ISS)
(3 more) |
|
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
|
13 |
O70129 (/ISS)
P0C7U5 (/ISS)
P30992 (/ISS)
P30993 (/ISS)
P79175 (/ISS)
P79188 (/ISS)
P79234 (/ISS)
P79240 (/ISS)
P79240 (/ISS)
P97520 (/ISS)
(3 more) |
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
9 | P21462 (/TAS) P21730 (/TAS) P25089 (/TAS) P25089 (/TAS) P25090 (/TAS) P25090 (/TAS) P46091 (/TAS) Q99788 (/TAS) Q9Y5Y4 (/TAS) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
7 | O08790 (/TAS) P21462 (/TAS) P21730 (/TAS) P25090 (/TAS) P25090 (/TAS) P33766 (/TAS) Q99788 (/TAS) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
6 | B1PHQ8 (/ISS) B1PHQ8 (/ISS) B9VR26 (/ISS) O35786 (/ISS) Q6XKD3 (/ISS) Q9Z2J6 (/ISS) |
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
6 | B1PHQ8 (/ISS) B1PHQ8 (/ISS) B9VR26 (/ISS) O35786 (/ISS) Q6XKD3 (/ISS) Q9Z2J6 (/ISS) |
|
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
|
6 | B1PHQ8 (/ISS) B1PHQ8 (/ISS) B9VR26 (/ISS) O35786 (/ISS) P97468 (/ISS) P97468 (/ISS) |
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
5 | O08790 (/IDA) P33766 (/IDA) Q71MR7 (/IDA) Q99788 (/IDA) Q9Y5Y4 (/IDA) |
|
Negative regulation of interleukin-12 production GO:0032695
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.
|
5 | B1PHQ8 (/ISS) B1PHQ8 (/ISS) B9VR26 (/ISS) O35786 (/ISS) Q99788 (/ISS) |
|
Positive regulation of fat cell differentiation GO:0045600
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
|
5 | B1PHQ8 (/ISS) B1PHQ8 (/ISS) B9VR26 (/ISS) O35786 (/ISS) Q99788 (/ISS) |
|
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
4 | P21462 (/TAS) P21730 (/TAS) P25089 (/TAS) P25089 (/TAS) |
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
4 | O88536 (/ISO) P97468 (/ISO) P97468 (/ISO) Q9Z2J6 (/ISO) |
|
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
|
4 | P21462 (/TAS) P21730 (/TAS) P25090 (/TAS) P25090 (/TAS) |
|
Regulation of calcium-mediated signaling GO:0050848
Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.
|
4 | B1PHQ8 (/ISS) B1PHQ8 (/ISS) B9VR26 (/ISS) O35786 (/ISS) |
|
Positive regulation of granulocyte chemotaxis GO:0071624
Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
|
4 | A0A060YND6 (/IDA) A0A060YND6 (/IDA) Q6UNA4 (/IDA) Q6UNA4 (/IDA) |
|
Cellular response to amyloid-beta GO:1904646
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.
|
4 | F1M670 (/IDA) O88536 (/IDA) P25090 (/IDA) P25090 (/IDA) |
|
Microglial cell activation GO:0001774
The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
3 | P21730 (/ISS) P25090 (/ISS) P25090 (/ISS) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
3 | Q99788 (/IDA) Q9Y5Y4 (/IDA) Q9Z2J6 (/IDA) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
3 | P97468 (/ISO) P97468 (/ISO) Q9Z2J6 (/ISO) |
|
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
3 | P21730 (/TAS) Q99788 (/TAS) Q9Y5Y4 (/TAS) |
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
3 | P25090 (/NAS) P25090 (/NAS) Q99788 (/NAS) |
|
Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
|
3 | F1M670 (/IGI) P25090 (/IGI) P25090 (/IGI) |
|
Phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
|
3 | O88536 (/IDA) P21462 (/IDA) P33766 (/IDA) |
|
Astrocyte activation GO:0048143
A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
3 | P21730 (/ISS) P25090 (/ISS) P25090 (/ISS) |
|
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
3 | F1M670 (/IGI) P25090 (/IGI) P25090 (/IGI) |
|
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
3 | G3V625 (/ISS) O35786 (/ISS) Q99788 (/ISS) |
|
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
|
2 | P21462 (/TAS) P21730 (/TAS) |
|
Microglial cell activation GO:0001774
The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
2 | F1M670 (/IGI) P30993 (/IGI) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
2 | P25090 (/IGI) P25090 (/IGI) |
|
Neutrophil activation involved in immune response GO:0002283
The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
|
2 | E7FF45 (/IMP) X1WBX3 (/IMP) |
|
Positive regulation of leukocyte chemotaxis GO:0002690
Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
|
2 | Q6UNA4 (/IMP) Q6UNA4 (/IMP) |
|
Immune response-regulating cell surface receptor signaling pathway GO:0002768
A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.
|
2 | P25090 (/IDA) P25090 (/IDA) |
|
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
2 | P25090 (/TAS) P25090 (/TAS) |
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
2 | P25090 (/TAS) P25090 (/TAS) |
|
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
2 | P25090 (/IDA) P25090 (/IDA) |
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
2 | P25090 (/IGI) P25090 (/IGI) |
|
Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
Positive regulation of macrophage chemotaxis GO:0010759
Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
|
2 | P30993 (/IMP) Q99788 (/IMP) |
|
Positive regulation of macrophage chemotaxis GO:0010759
Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
|
2 | P97468 (/ISO) P97468 (/ISO) |
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | Q9Y5Y4 (/IDA) Q9Z2J6 (/IDA) |
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | P25090 (/IGI) P25090 (/IGI) |
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | O88536 (/ISO) Q9Z2J6 (/ISO) |
|
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
|
2 | P97468 (/ISO) P97468 (/ISO) |
|
Negative regulation of interleukin-12 production GO:0032695
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.
|
2 | P97468 (/IMP) P97468 (/IMP) |
|
Positive regulation of superoxide anion generation GO:0032930
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
2 | P25090 (/IDA) P25090 (/IDA) |
|
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
|
2 | P25090 (/IDA) P25090 (/IDA) |
|
Positive regulation of fat cell differentiation GO:0045600
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
|
2 | P97468 (/IMP) P97468 (/IMP) |
|
Astrocyte activation GO:0048143
A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
2 | F1M670 (/IGI) P30993 (/IGI) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
2 | P25090 (/IDA) P25090 (/IDA) |
|
Positive regulation of phagocytosis GO:0050766
Any process that activates or increases the frequency, rate or extent of phagocytosis.
|
2 | P25090 (/IDA) P25090 (/IDA) |
|
Regulation of calcium-mediated signaling GO:0050848
Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.
|
2 | P97468 (/ISO) P97468 (/ISO) |
|
Positive chemotaxis GO:0050918
The directed movement of a motile cell or organism towards a higher concentration of a chemical.
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
Positive regulation of 1-phosphatidylinositol-3-kinase activity GO:0061903
Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
2 | O88536 (/ISO) P30993 (/ISO) |
|
Positive regulation of monocyte chemotaxis GO:0090026
Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
|
2 | P25090 (/IGI) P25090 (/IGI) |
|
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
2 | P97468 (/IMP) P97468 (/IMP) |
|
Cellular response to amyloid-beta GO:1904646
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.
|
2 | P25090 (/ISS) P25090 (/ISS) |
|
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
1 | Q99788 (/TAS) |
|
Microglial cell activation GO:0001774
The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
1 | O88536 (/ISO) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
1 | O88536 (/ISO) |
|
Immune response-regulating cell surface receptor signaling pathway GO:0002768
A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.
|
1 | O88536 (/ISO) |
|
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | F1M670 (/IMP) |
|
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | O88536 (/ISO) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
1 | P97520 (/IMP) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
1 | P30993 (/ISO) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | P97520 (/IEP) |
|
Cellular defense response GO:0006968
A defense response that is mediated by cells.
|
1 | P21730 (/TAS) |
|
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
1 | O88536 (/ISO) |
|
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007188
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP).
|
1 | P21462 (/TAS) |
|
Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
|
1 | Q9Z2J6 (/IDA) |
|
Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
|
1 | O88536 (/ISO) |
|
Phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
|
1 | P33766 (/ISO) |
|
Activation of phospholipase C activity GO:0007202
The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.
|
1 | P21730 (/TAS) |
|
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
1 | P97520 (/IDA) |
|
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
1 | P30993 (/ISO) |
|
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
1 | P21730 (/TAS) |
|
Nitric oxide mediated signal transduction GO:0007263
Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.
|
1 | P21462 (/TAS) |
|
Sensory perception of chemical stimulus GO:0007606
The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
1 | P21730 (/TAS) |
|
Positive regulation of vascular endothelial growth factor production GO:0010575
Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
|
1 | P30993 (/IMP) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P21462 (/TAS) |
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
1 | Q6XKD3 (/ISS) |
|
Cell proliferation in hindbrain GO:0021534
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.
|
1 | P97520 (/IMP) |
|
Cell proliferation in hindbrain GO:0021534
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.
|
1 | P30993 (/ISO) |
|
Regulation of complement activation GO:0030449
Any process that modulates the frequency, rate or extent of complement activation.
|
1 | P21730 (/TAS) |
|
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | P30993 (/IMP) |
|
Animal organ regeneration GO:0031100
The regrowth of a lost or destroyed animal organ.
|
1 | P97520 (/IEP) |
|
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
|
1 | Q99788 (/IDA) |
|
Response to peptidoglycan GO:0032494
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
|
1 | P30993 (/IMP) |
|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | P97520 (/IEP) |
|
Positive regulation of superoxide anion generation GO:0032930
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
|
1 | O88536 (/IGI) |
|
Complement component C5a signaling pathway GO:0038178
A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.
|
1 | P21730 (/IDA) |
|
Complement component C5a signaling pathway GO:0038178
A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.
|
1 | P30993 (/ISO) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | O88536 (/ISO) |
|
MRNA transcription by RNA polymerase II GO:0042789
The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
|
1 | P21730 (/IDA) |
|
MRNA transcription by RNA polymerase II GO:0042789
The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
|
1 | P30993 (/ISO) |
|
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
1 | P97520 (/IDA) |
|
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
1 | P97520 (/IMP) |
|
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
1 | P30993 (/ISO) |
|
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
|
1 | O88536 (/ISO) |
|
Positive regulation of G protein-coupled receptor signaling pathway GO:0045745
Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
|
1 | O88536 (/IC) |
|
Positive regulation of G protein-coupled receptor signaling pathway GO:0045745
Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
|
1 | Q9Z2J6 (/IDA) |
|
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
1 | P30993 (/IMP) |
|
Astrocyte activation GO:0048143
A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
1 | O88536 (/ISO) |
|
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
|
1 | P21730 (/IDA) |
|
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
|
1 | P30993 (/ISO) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
1 | O88536 (/ISO) |
|
Positive regulation of phagocytosis GO:0050766
Any process that activates or increases the frequency, rate or extent of phagocytosis.
|
1 | O88536 (/ISO) |
|
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
|
1 | P30993 (/IMP) |
|
Regulation of calcium-mediated signaling GO:0050848
Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.
|
1 | Q99788 (/IDA) |
|
Cognition GO:0050890
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
|
1 | P30993 (/IGI) |
|
Cognition GO:0050890
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
|
1 | P21730 (/ISS) |
|
Positive chemotaxis GO:0050918
The directed movement of a motile cell or organism towards a higher concentration of a chemical.
|
1 | O88536 (/IGI) |
|
Positive regulation of 1-phosphatidylinositol-3-kinase activity GO:0061903
Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.
|
1 | F1M670 (/IGI) |
|
Positive regulation of 1-phosphatidylinositol-3-kinase activity GO:0061903
Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.
|
1 | O88536 (/ISO) |
|
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | P21730 (/IDA) |
|
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | F1M670 (/IMP) |
|
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | P30993 (/IMP) |
|
Positive regulation of monocyte chemotaxis GO:0090026
Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
|
1 | O88536 (/ISO) |
|
Amyloid-beta clearance GO:0097242
The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.
|
1 | P30993 (/IGI) |
|
Amyloid-beta clearance GO:0097242
The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.
|
1 | P21730 (/ISS) |
|
Presynapse organization GO:0099172
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.
|
1 | P30993 (/IGI) |
|
Presynapse organization GO:0099172
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.
|
1 | P21730 (/ISS) |
|
Regulation of tau-protein kinase activity GO:1902947
Any process that modulates the frequency, rate or extent of tau-protein kinase activity.
|
1 | P30993 (/IGI) |
|
Regulation of tau-protein kinase activity GO:1902947
Any process that modulates the frequency, rate or extent of tau-protein kinase activity.
|
1 | P21730 (/ISS) |
|
Cellular response to amyloid-beta GO:1904646
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.
|
1 | O88536 (/ISO) |
|
Negative regulation of male germ cell proliferation GO:2000255
Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.
|
1 | Q9Z2J6 (/IMP) |
There are 31 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
13 |
O70129 (/ISS)
P0C7U5 (/ISS)
P30992 (/ISS)
P30993 (/ISS)
P79175 (/ISS)
P79188 (/ISS)
P79234 (/ISS)
P79240 (/ISS)
P79240 (/ISS)
P97520 (/ISS)
(3 more) |
|
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
13 |
O70129 (/ISS)
P0C7U5 (/ISS)
P30992 (/ISS)
P30993 (/ISS)
P79175 (/ISS)
P79188 (/ISS)
P79234 (/ISS)
P79240 (/ISS)
P79240 (/ISS)
P97520 (/ISS)
(3 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
8 | P21462 (/TAS) P21730 (/TAS) P25089 (/TAS) P25089 (/TAS) P25090 (/TAS) P25090 (/TAS) Q99788 (/TAS) Q9Y5Y4 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | D4A7Q2 (/IDA) F1M670 (/IDA) P25090 (/IDA) P25090 (/IDA) P46091 (/IDA) P97520 (/IDA) Q99788 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | B1PHQ8 (/ISS) B1PHQ8 (/ISS) B9VR26 (/ISS) O35786 (/ISS) P21462 (/ISS) P25090 (/ISS) P25090 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | O88536 (/ISO) P30993 (/ISO) P33766 (/ISO) P97468 (/ISO) P97468 (/ISO) Q8K087 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | P21462 (/TAS) P25089 (/TAS) P25089 (/TAS) P25090 (/TAS) P25090 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | D4A7Q2 (/IDA) F1M670 (/IDA) P25090 (/IDA) P25090 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | P21730 (/TAS) P46091 (/TAS) Q99788 (/TAS) Q9Y5Y4 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | P21462 (/ISS) P25090 (/ISS) P25090 (/ISS) |
|
Ficolin-1-rich granule membrane GO:0101003
The lipid bilayer surrounding a ficolin-1-rich granule.
|
3 | P21462 (/TAS) P25090 (/TAS) P25090 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | O88536 (/ISO) P33766 (/ISO) |
|
Secretory granule membrane GO:0030667
The lipid bilayer surrounding a secretory granule.
|
2 | P21462 (/TAS) P21730 (/TAS) |
|
Specific granule membrane GO:0035579
The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
|
2 | P25090 (/TAS) P25090 (/TAS) |
|
Tertiary granule membrane GO:0070821
The lipid bilayer surrounding a tertiary granule.
|
2 | P25090 (/TAS) P25090 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | P46091 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8K087 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | C1BI79 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q71MR7 (/IC) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9Z2J6 (/ISS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P97520 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P30993 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q99788 (/NAS) |
|
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
1 | P21730 (/IDA) |
|
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
1 | P30993 (/ISO) |
|
Azurophil granule membrane GO:0035577
The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
|
1 | P21462 (/TAS) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | P46091 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q8K087 (/ISO) |
|
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
1 | P21730 (/IDA) |
|
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
1 | P30993 (/ISO) |
|
Yolk GO:0060417
The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.
|
1 | C1BI79 (/IDA) |
