The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Rhodopsin 7-helix transmembrane proteins
".
FunFam 264: 5-hydroxytryptamine receptor 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
G protein-coupled serotonin receptor activity GO:0004993
Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
|
2 | P20905 (/IDA) P20905 (/IDA) |
|
G protein-coupled serotonin receptor activity GO:0004993
Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
|
2 | P20905 (/ISS) P20905 (/ISS) |
|
G protein-coupled serotonin receptor activity GO:0004993
Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
|
2 | P20905 (/TAS) P20905 (/TAS) |
|
G protein-coupled amine receptor activity GO:0008227
Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
2 | P20905 (/ISS) P20905 (/ISS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Adenylate cyclase-activating serotonin receptor signaling pathway GO:0007192
The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
|
2 | P20905 (/TAS) P20905 (/TAS) |
|
Serotonin receptor signaling pathway GO:0007210
The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.
|
2 | P20905 (/IDA) P20905 (/IDA) |
|
Serotonin receptor signaling pathway GO:0007210
The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.
|
2 | P20905 (/ISS) P20905 (/ISS) |
|
Courtship behavior GO:0007619
The behavioral interactions between organisms for the purpose of attracting sexual partners.
|
2 | P20905 (/IMP) P20905 (/IMP) |
|
Male courtship behavior, orientation prior to leg tapping and wing vibration GO:0016543
The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster.
|
2 | P20905 (/IMP) P20905 (/IMP) |
|
Male courtship behavior, veined wing vibration GO:0016545
The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster.
|
2 | P20905 (/IMP) P20905 (/IMP) |
|
Male courtship behavior, proboscis-mediated licking GO:0016546
The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster.
|
2 | P20905 (/IMP) P20905 (/IMP) |
|
Male mating behavior GO:0060179
The specific behavior of a male organism that is associated with reproduction.
|
2 | P20905 (/IMP) P20905 (/IMP) |
|
Female mating behavior GO:0060180
The specific behavior of a female organism that is associated with reproduction.
|
2 | P20905 (/IMP) P20905 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | P20905 (/ISS) P20905 (/ISS) |
