The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhodopsin 7-helix transmembrane proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 160: Related to Opsin-1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
All-trans retinal binding GO:0005503
Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
1 Q9UW81 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
5 P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP)
Negative regulation of ATPase activity GO:0032780
Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
5 P25619 (/IMP) P25619 (/IMP) P25619 (/IMP) P25619 (/IMP) P25619 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
5 P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
5 P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP)
Cellular response to ethanol GO:0071361
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
5 P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
5 P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP) P25619 (/IEP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
1 Q9UW81 (/NAS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
19 P25619 (/IDA) P25619 (/IDA) P25619 (/IDA) P25619 (/IDA) P25619 (/IDA) P38079 (/IDA) P38079 (/IDA) P38079 (/IDA) Q12117 (/IDA) Q12117 (/IDA)
(9 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
16 P25619 (/HDA) P25619 (/HDA) P25619 (/HDA) P25619 (/HDA) P25619 (/HDA) P38079 (/HDA) P38079 (/HDA) P38079 (/HDA) Q12117 (/HDA) Q12117 (/HDA)
(6 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
13 P25619 (/HDA) P25619 (/HDA) P25619 (/HDA) P25619 (/HDA) P25619 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA)
(3 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
11 P38079 (/HDA) P38079 (/HDA) P38079 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA) Q12117 (/HDA)
(1 more)
Cellular bud GO:0005933
A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.
3 P38079 (/HDA) P38079 (/HDA) P38079 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O74870 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 O74870 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9UW81 (/NAS)
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