The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhodopsin 7-helix transmembrane proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 104: Opsin 5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
11-cis retinal binding GO:0005502
Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
All-trans retinal binding GO:0005503
Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
G protein-coupled photoreceptor activity GO:0008020
Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
11-cis retinal binding GO:0005502
Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
5 B3XZF5 (/IDA) E6P6L8 (/IDA) F1NEY2 (/IDA) Q5RIV6 (/IDA) Q6VZZ7 (/IDA)
All-trans retinal binding GO:0005503
Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
4 B3XZF5 (/IDA) E6P6L8 (/IDA) F1NEY2 (/IDA) Q5RIV6 (/IDA)
G protein-coupled photoreceptor activity GO:0008020
Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2 B3XZF5 (/IDA) F1NEY2 (/IDA)
Heterotrimeric G-protein binding GO:0032795
Interacting selectively and non-covalently with a heterotrimeric G-protein.
2 B3XZF5 (/IC) F1NEY2 (/IC)
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1 Q6VZZ7 (/IDA)
Photoreceptor activity GO:0009881
The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
1 D9N3D0 (/IMP)
Light-activated ion channel activity GO:0010461
Enables the transmembrane transfer of an ion by a channel that opens in response to a light stimulus.
1 D9N3D0 (/IMP)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Absorption of visible light GO:0016038
The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
Absorption of UV light GO:0016039
The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
Protein-chromophore linkage GO:0018298
The covalent or noncovalent attachment of a chromophore to a protein.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
Absorption of visible light GO:0016038
The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
4 B3XZF5 (/IDA) E6P6L8 (/IDA) F1NEY2 (/IDA) Q5RIV6 (/IDA)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
2 F1R302 (/IDA) Q5TZG0 (/IDA)
Absorption of UV light GO:0016039
The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
2 B3XZF5 (/IDA) F1NEY2 (/IDA)
Protein-chromophore linkage GO:0018298
The covalent or noncovalent attachment of a chromophore to a protein.
2 B3XZF5 (/IDA) F1NEY2 (/IDA)
Phototransduction, visible light GO:0007603
The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
1 D9N3D0 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
7 D8KW68 (/ISS) D8KWH6 (/ISS) D9N3D0 (/ISS) G1NNA7 (/ISS) R0LKL2 (/ISS) U3J4Q3 (/ISS) U3JFW4 (/ISS)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
2 B3XZF5 (/IDA) F1NEY2 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 B3XZF5 (/IDA) F1NEY2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 B3XZF5 (/IDA) F1NEY2 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
2 B3XZF5 (/IDA) F1NEY2 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 D9N3D0 (/IC)
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