The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TAZ domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: E1A binding protein p300

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 104 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
8 A0A0R4IPF3 (/IDA) A0A0R4IUG1 (/IDA) B2RWS6 (/IDA) P34545 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q6JHU9 (/IDA) Q92793 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 B2RWS6 (/IPI) E1B8D6 (/IPI) F1RK46 (/IPI) P45481 (/IPI) Q09472 (/IPI) Q6JHU9 (/IPI) Q92793 (/IPI)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
6 A0A0G2QC09 (/IPI) B2RWS6 (/IPI) P34545 (/IPI) P45481 (/IPI) Q09472 (/IPI) Q92793 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
4 B2RWS6 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q92793 (/IDA)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
4 P45481 (/IDA) Q09472 (/IDA) Q8BJ14 (/IDA) Q92793 (/IDA)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
4 P45481 (/TAS) Q09472 (/TAS) Q6JHU9 (/TAS) Q92793 (/TAS)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
4 B2RWS6 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q92793 (/IDA)
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
3 B2RWS6 (/IPI) P45481 (/IPI) Q92793 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 B2RWS6 (/IDA) P45481 (/IDA) Q09472 (/IDA)
Damaged DNA binding GO:0003684
Interacting selectively and non-covalently with damaged DNA.
3 B2RWS6 (/ISS) P45481 (/ISS) Q6JHU9 (/ISS)
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
3 B2RWS6 (/ISS) P45481 (/ISS) Q6JHU9 (/ISS)
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
3 P45481 (/TAS) Q09472 (/TAS) Q92793 (/TAS)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
3 B2RWS6 (/ISS) P45481 (/ISS) Q6JHU9 (/ISS)
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
3 Q09472 (/IPI) Q6JHU9 (/IPI) Q8BJ14 (/IPI)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
2 P45481 (/IDA) Q09472 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
2 B2RWS6 (/IDA) Q09472 (/IDA)
Proximal promoter sequence-specific DNA binding GO:0000987
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.
2 B2RWS6 (/ISO) P45481 (/ISO)
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
2 B2RWS6 (/IPI) Q09472 (/IPI)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 B2RWS6 (/IDA) P45481 (/IDA)
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
2 B2RWS6 (/IPI) Q92793 (/IPI)
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
2 B2RWS6 (/ISO) P45481 (/ISO)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
2 B2RWS6 (/ISO) P45481 (/ISO)
Damaged DNA binding GO:0003684
Interacting selectively and non-covalently with damaged DNA.
2 Q09472 (/IDA) Q92793 (/IDA)
Damaged DNA binding GO:0003684
Interacting selectively and non-covalently with damaged DNA.
2 B2RWS6 (/ISO) P45481 (/ISO)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
2 B2RWS6 (/IMP) Q09472 (/IMP)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
2 Q09472 (/IPI) Q92793 (/IPI)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
2 B2RWS6 (/ISO) P45481 (/ISO)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
2 B2RWS6 (/ISS) P45481 (/ISS)
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
2 B2RWS6 (/ISO) P45481 (/ISO)
Lysine N-acetyltransferase activity, acting on acetyl phosphate as donor GO:0004468
Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.
2 P34545 (/IDA) Q09472 (/IDA)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
2 B2RWS6 (/ISO) P45481 (/ISO)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
2 Q09472 (/EXP) Q92793 (/EXP)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
2 B2RWS6 (/ISO) P45481 (/ISO)
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
2 B2RWS6 (/ISO) P45481 (/ISO)
Peroxisome proliferator activated receptor binding GO:0042975
Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma.
2 B2RWS6 (/ISO) P45481 (/ISO)
MRF binding GO:0043426
Interacting selectively and non-covalently with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.
2 P45481 (/ISS) Q6JHU9 (/ISS)
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
2 B2RWS6 (/ISO) P45481 (/ISO)
Peptide-lysine-N-acetyltransferase activity GO:0061733
Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.
2 P45481 (/TAS) Q09472 (/TAS)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
1 B2RWS6 (/ISO)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 B2RWS6 (/ISO)
Proximal promoter sequence-specific DNA binding GO:0000987
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q92793 (/IDA)
Core promoter sequence-specific DNA binding GO:0001046
Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
1 F1NGB5 (/IDA)
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
1 P45481 (/ISO)
TFIIB-class transcription factor binding GO:0001093
Interacting selectively and non-covalently with a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
1 P45481 (/IPI)
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
1 B2RWS6 (/ISO)
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
1 Q92793 (/TAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 B2RWS6 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 B2RWS6 (/ISS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q09472 (/IMP)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q6JHU9 (/ISS)
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
1 P34545 (/ISS)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
1 A0A0G2QC09 (/IGI)
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
1 Q92793 (/IDA)
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
1 P45481 (/ISO)
Antigen binding GO:0003823
Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
1 B2RWS6 (/ISO)
Lysine N-acetyltransferase activity, acting on acetyl phosphate as donor GO:0004468
Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.
1 B2RWS6 (/ISO)
Lysine N-acetyltransferase activity, acting on acetyl phosphate as donor GO:0004468
Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.
1 B2RWS6 (/ISS)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 Q09472 (/IPI)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 B2RWS6 (/ISO)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q09472 (/IDA)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 B2RWS6 (/ISO)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
1 P45481 (/ISS)
CAMP response element binding protein binding GO:0008140
Interacting selectively and non-covalently with a cAMP response element binding protein (a CREB protein).
1 P45481 (/IPI)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 P45481 (/IMP)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
1 Q09472 (/IMP)
Transferase activity, transferring acyl groups GO:0016746
Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
1 Q09472 (/IDA)
Transferase activity, transferring acyl groups GO:0016746
Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
1 B2RWS6 (/ISO)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 B2RWS6 (/ISO)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 P45481 (/IPI)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 B2RWS6 (/IDA)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 B2RWS6 (/ISO)
Nuclear hormone receptor binding GO:0035257
Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.
1 Q09472 (/IPI)
Nuclear hormone receptor binding GO:0035257
Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.
1 B2RWS6 (/ISO)
Glucocorticoid receptor binding GO:0035259
Interacting selectively and non-covalently with a glucocorticoid receptor.
1 B2RWS6 (/ISO)
Peroxisome proliferator activated receptor binding GO:0042975
Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma.
1 Q6JHU9 (/IDA)
BHLH transcription factor binding GO:0043425
Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
1 B2RWS6 (/ISO)
MRF binding GO:0043426
Interacting selectively and non-covalently with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.
1 Q92793 (/IDA)
MRF binding GO:0043426
Interacting selectively and non-covalently with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.
1 P45481 (/ISO)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 B2RWS6 (/ISO)
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
1 Q6JHU9 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 P45481 (/IMP)
Tau protein binding GO:0048156
Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
1 Q09472 (/NAS)
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
1 Q09472 (/IPI)
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
1 B2RWS6 (/ISO)
Mitogen-activated protein kinase binding GO:0051019
Interacting selectively and non-covalently with a mitogen-activated protein kinase.
1 B2RWS6 (/ISO)
NF-kappaB binding GO:0051059
Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.
1 Q09472 (/IPI)
NF-kappaB binding GO:0051059
Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.
1 B2RWS6 (/ISO)
RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629
Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.
1 P34545 (/IPI)
Peptide-lysine-N-acetyltransferase activity GO:0061733
Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.
1 P34545 (/IDA)
Protein propionyltransferase activity GO:0061920
Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.
1 Q09472 (/IDA)
Protein propionyltransferase activity GO:0061920
Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.
1 B2RWS6 (/ISO)
Protein propionyltransferase activity GO:0061920
Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.
1 B2RWS6 (/ISS)
Pre-mRNA intronic binding GO:0097157
Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA).
1 B2RWS6 (/IDA)
STAT family protein binding GO:0097677
Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.
1 Q09472 (/IPI)
STAT family protein binding GO:0097677
Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.
1 B2RWS6 (/ISO)
Disordered domain specific binding GO:0097718
Interacting selectively and non-covalently with a disordered domain of a protein.
1 P45481 (/IPI)
Peptide butyryltransferase activity GO:0140065
Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.
1 Q09472 (/IDA)
Peptide butyryltransferase activity GO:0140065
Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.
1 B2RWS6 (/ISO)
Histone crotonyltransferase activity GO:0140068
Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.
1 Q09472 (/IDA)
Histone crotonyltransferase activity GO:0140068
Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.
1 B2RWS6 (/ISO)
Histone crotonyltransferase activity GO:0140068
Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.
1 B2RWS6 (/ISS)
Histone butyryltransferase activity GO:0140069
Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone.
1 B2RWS6 (/IDA)
Protein antigen binding GO:1990405
Interacting selectively and non-covalently with a protein antigen.
1 B2RWS6 (/ISO)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
1 B2RWS6 (/ISO)

There are 204 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
5 B2RWS6 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q6JHU9 (/IDA) Q92793 (/IDA)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
5 B2RWS6 (/IDA) P34545 (/IDA) Q09472 (/IDA) Q6JHU9 (/IDA) Q92793 (/IDA)
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
4 A0A0R4IPF3 (/IGI) A0A0R4IUG1 (/IGI) F1R259 (/IGI) X1WG57 (/IGI)
Pectoral fin development GO:0033339
The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.
4 A0A0R4IPF3 (/IGI) A0A0R4IUG1 (/IGI) F1R259 (/IGI) X1WG57 (/IGI)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
4 A0A0R4IPF3 (/IGI) A0A0R4IUG1 (/IGI) F1R259 (/IGI) X1WG57 (/IGI)
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
3 A0A0R4INM9 (/IMP) A0A0R4IPF2 (/IMP) A0A2R8Q4T2 (/IMP)
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
3 B2RWS6 (/IDA) Q09472 (/IDA) Q92793 (/IDA)
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
3 B2RWS6 (/ISS) P45481 (/ISS) Q6JHU9 (/ISS)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
3 B2RWS6 (/ISS) P45481 (/ISS) Q6JHU9 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 B2RWS6 (/IDA) P45481 (/IDA) Q92793 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 P45481 (/ISS) Q6JHU9 (/ISS) Q92793 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 B2RWS6 (/IGI) P34545 (/IGI) P45481 (/IGI)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 Q09472 (/IDA) Q92793 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 B2RWS6 (/ISO) P45481 (/ISO)
Stimulatory C-type lectin receptor signaling pathway GO:0002223
Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.
2 Q09472 (/TAS) Q92793 (/TAS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 B2RWS6 (/ISO) P45481 (/ISO)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 P34545 (/TAS) Q92793 (/TAS)
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
2 B2RWS6 (/ISO) P45481 (/ISO)
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
2 Q09472 (/TAS) Q92793 (/TAS)
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 Q09472 (/TAS) Q92793 (/TAS)
Positive regulation of transcription of Notch receptor target GO:0007221
The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.
2 Q09472 (/TAS) Q92793 (/TAS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 B2RWS6 (/IGI) P45481 (/IGI)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
2 B2RWS6 (/ISO) P45481 (/ISO)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
2 P45481 (/ISS) Q6JHU9 (/ISS)
N-terminal peptidyl-lysine acetylation GO:0018076
The acetylation of the N-terminal lysine of proteins.
2 Q09472 (/IDA) Q92793 (/IDA)
N-terminal peptidyl-lysine acetylation GO:0018076
The acetylation of the N-terminal lysine of proteins.
2 B2RWS6 (/ISO) P45481 (/ISO)
N-terminal peptidyl-lysine acetylation GO:0018076
The acetylation of the N-terminal lysine of proteins.
2 B2RWS6 (/ISS) P45481 (/ISS)
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
2 P34545 (/IDA) Q09472 (/IDA)
Positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511
Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.
2 Q09472 (/IMP) Q92793 (/IMP)
Positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511
Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.
2 B2RWS6 (/ISO) P45481 (/ISO)
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
2 Q09472 (/IMP) Q92793 (/IMP)
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
2 B2RWS6 (/ISO) P45481 (/ISO)
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
2 Q09472 (/TAS) Q92793 (/TAS)
Pectoral fin development GO:0033339
The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.
2 A0A0R4IPF3 (/IMP) A0A0R4IUG1 (/IMP)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
2 Q09472 (/IDA) Q92793 (/IDA)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
2 B2RWS6 (/ISO) P45481 (/ISO)
Positive regulation of Notch signaling pathway GO:0045747
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
2 Q09472 (/TAS) Q92793 (/TAS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 B2RWS6 (/IDA) Q09472 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q09472 (/IMP) Q6JHU9 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 B2RWS6 (/ISO) P45481 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q09472 (/TAS) Q92793 (/TAS)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
2 A0A0R4IPF3 (/IMP) A0A0R4IUG1 (/IMP)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
2 B2RWS6 (/IDA) Q09472 (/IDA)
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
2 B2RWS6 (/IMP) P45481 (/IMP)
Regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061418
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
2 Q09472 (/TAS) Q92793 (/TAS)
Peptidyl-lysine butyrylation GO:0140067
The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid.
2 B2RWS6 (/IDA) Q09472 (/IDA)
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
2 Q09472 (/TAS) Q92793 (/TAS)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
2 B2RWS6 (/ISO) P45481 (/ISO)
Beta-catenin-TCF complex assembly GO:1904837
The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.
2 Q09472 (/TAS) Q92793 (/TAS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 B2RWS6 (/ISS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 Q09472 (/IDA)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 B2RWS6 (/ISO)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 B2RWS6 (/ISS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 Q92793 (/TAS)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
1 B2RWS6 (/IGI)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
1 B2RWS6 (/ISO)
Thigmotaxis GO:0001966
The directed movement of a motile cell or organism in response to touch.
1 B2RWS6 (/IMP)
Behavioral defense response GO:0002209
A behavioral response seeking to protect an organism from an a perceived external threat to that organism.
1 B2RWS6 (/IMP)
Transcription-coupled nucleotide-excision repair GO:0006283
The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
1 Q09472 (/TAS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 P45481 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 B2RWS6 (/ISS)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
1 Q92793 (/TAS)
Internal protein amino acid acetylation GO:0006475
The addition of an acetyl group to a non-terminal amino acid in a protein.
1 Q09472 (/IDA)
Internal protein amino acid acetylation GO:0006475
The addition of an acetyl group to a non-terminal amino acid in a protein.
1 B2RWS6 (/ISO)
Internal protein amino acid acetylation GO:0006475
The addition of an acetyl group to a non-terminal amino acid in a protein.
1 B2RWS6 (/ISS)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 Q09472 (/IMP)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 B2RWS6 (/ISO)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 B2RWS6 (/ISS)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
1 Q09472 (/TAS)
Positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response GO:0006990
The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response.
1 B2RWS6 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response GO:0006990
The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response.
1 Q09472 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q92793 (/NAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q92793 (/TAS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 P34545 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
1 Q09472 (/TAS)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 B2RWS6 (/IMP)
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
1 B2RWS6 (/IMP)
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
1 B2RWS6 (/IMP)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 B2RWS6 (/IDA)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 Q09472 (/ISS)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q6JHU9 (/IDA)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 P45481 (/ISO)
Regulation of smoothened signaling pathway GO:0008589
Any process that modulates the frequency, rate or extent of smoothened signaling.
1 Q92793 (/TAS)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 F1NGB5 (/IDA)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 B2RWS6 (/ISO)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 P34545 (/IMP)
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 B2RWS6 (/IMP)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 Q09472 (/TAS)
Positive regulation of glycoprotein biosynthetic process GO:0010560
Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
1 B2RWS6 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 E1B8D6 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 B2RWS6 (/ISO)
Macrophage derived foam cell differentiation GO:0010742
The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
1 Q09472 (/IDA)
Macrophage derived foam cell differentiation GO:0010742
The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
1 B2RWS6 (/ISO)
Macrophage derived foam cell differentiation GO:0010742
The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
1 B2RWS6 (/ISS)
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 B2RWS6 (/ISO)
Regulation of neuron projection development GO:0010975
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 P34545 (/IMP)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q09472 (/IDA)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 B2RWS6 (/ISO)
Positive regulation of muscle atrophy GO:0014737
Any process that activates or increases the frequency, rate or extent of muscle atrophy.
1 B2RWS6 (/ISO)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
1 Q09472 (/TAS)
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
1 B2RWS6 (/ISO)
Peptidyl-lysine acetylation GO:0018394
The acetylation of peptidyl-lysine.
1 Q09472 (/IDA)
Peptidyl-lysine acetylation GO:0018394
The acetylation of peptidyl-lysine.
1 B2RWS6 (/ISO)
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
1 Q92793 (/TAS)
B cell differentiation GO:0030183
The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
1 B2RWS6 (/IMP)
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
1 B2RWS6 (/IGI)
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
1 B2RWS6 (/IMP)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
1 B2RWS6 (/ISO)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
1 B2RWS6 (/IMP)
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
1 P45481 (/IMP)
Negative regulation of cellular metabolic process GO:0031324
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
1 B2RWS6 (/ISO)
Positive regulation of cellular metabolic process GO:0031325
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
1 B2RWS6 (/ISO)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 B2RWS6 (/IDA)
Negative regulation of protein oligomerization GO:0032460
Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.
1 Q09472 (/IDA)
Negative regulation of protein oligomerization GO:0032460
Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.
1 B2RWS6 (/ISO)
Positive regulation of CREB transcription factor activity GO:0032793
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.
1 P45481 (/IDA)
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
1 B2RWS6 (/ISO)
Positive regulation of histone acetylation GO:0035066
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.
1 B2RWS6 (/ISO)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 B2RWS6 (/IMP)
Cellular response to hepatocyte growth factor stimulus GO:0035729
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
1 P45481 (/IDA)
Megakaryocyte development GO:0035855
The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.
1 B2RWS6 (/IMP)
Swimming GO:0036268
Self-propelled movement of an organism from one location to another through water, often by means of active fin movement.
1 B2RWS6 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 B2RWS6 (/ISO)
Homeostatic process GO:0042592
Any biological process involved in the maintenance of an internal steady state.
1 Q92793 (/NAS)
Embryonic digit morphogenesis GO:0042733
The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.
1 Q92793 (/TAS)
Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
1 Q09472 (/IDA)
Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
1 B2RWS6 (/ISO)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
1 Q92793 (/TAS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 P34545 (/IMP)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
1 B2RWS6 (/ISO)
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
1 B2RWS6 (/ISO)
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
1 B2RWS6 (/ISO)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 Q09472 (/IDA)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 B2RWS6 (/ISO)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 B2RWS6 (/ISS)
Positive regulation by host of viral transcription GO:0043923
Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
1 Q09472 (/IDA)
Positive regulation by host of viral transcription GO:0043923
Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
1 B2RWS6 (/ISO)
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
1 B2RWS6 (/ISO)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
1 Q09472 (/IMP)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
1 B2RWS6 (/ISO)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
1 B2RWS6 (/ISS)
Histone H2B acetylation GO:0043969
The modification of histone H2B by the addition of an acetyl group.
1 Q09472 (/IDA)
Histone H2B acetylation GO:0043969
The modification of histone H2B by the addition of an acetyl group.
1 B2RWS6 (/ISO)
Histone H2B acetylation GO:0043969
The modification of histone H2B by the addition of an acetyl group.
1 B2RWS6 (/ISS)
Negative regulation of interferon-beta biosynthetic process GO:0045358
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta.
1 P45481 (/IMP)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
1 B2RWS6 (/IMP)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
1 Q09472 (/ISS)
Regulation of myeloid cell differentiation GO:0045637
Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
1 Q92793 (/TAS)
Regulation of megakaryocyte differentiation GO:0045652
Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
1 Q09472 (/TAS)
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
1 Q09472 (/IDA)
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
1 B2RWS6 (/ISO)
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 B2RWS6 (/ISO)
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
1 B2RWS6 (/ISO)
Positive regulation of cell size GO:0045793
Any process that increases cell size.
1 B2RWS6 (/ISO)
Positive regulation of gene expression, epigenetic GO:0045815
Any epigenetic process that activates or increases the rate of gene expression.
1 Q09472 (/IDA)
Positive regulation of gene expression, epigenetic GO:0045815
Any epigenetic process that activates or increases the rate of gene expression.
1 B2RWS6 (/ISO)
Positive regulation of gene expression, epigenetic GO:0045815
Any epigenetic process that activates or increases the rate of gene expression.
1 B2RWS6 (/ISS)
Positive regulation of gene expression, epigenetic GO:0045815
Any epigenetic process that activates or increases the rate of gene expression.
1 Q09472 (/TAS)
Positive regulation of proteolysis GO:0045862
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
1 B2RWS6 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P45481 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q09472 (/TAS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 B2RWS6 (/ISS)
Negative regulation of viral process GO:0048525
Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.
1 P45481 (/IMP)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
1 B2RWS6 (/ISO)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
1 B2RWS6 (/IDA)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
1 Q09472 (/ISS)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 B2RWS6 (/ISO)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 B2RWS6 (/ISS)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 P45481 (/TAS)
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
1 B2RWS6 (/NAS)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 B2RWS6 (/ISO)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 Q09472 (/TAS)
Regulation of angiotensin metabolic process GO:0060177
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin.
1 B2RWS6 (/ISO)
Positive regulation of sarcomere organization GO:0060298
Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
1 B2RWS6 (/ISO)
Positive regulation of cell adhesion molecule production GO:0060355
Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
1 Q6JHU9 (/IMP)
Positive regulation of cell adhesion molecule production GO:0060355
Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
1 P45481 (/ISO)
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 B2RWS6 (/ISO)
Regulation of androgen receptor signaling pathway GO:0060765
Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.
1 Q09472 (/IDA)
Regulation of androgen receptor signaling pathway GO:0060765
Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.
1 B2RWS6 (/ISO)
Positive regulation of cell growth involved in cardiac muscle cell development GO:0061051
Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
1 B2RWS6 (/ISO)
Peptidyl-lysine propionylation GO:0061921
The propionylation of peptidyl-lysine.
1 Q09472 (/IDA)
Peptidyl-lysine propionylation GO:0061921
The propionylation of peptidyl-lysine.
1 B2RWS6 (/ISO)
Peptidyl-lysine propionylation GO:0061921
The propionylation of peptidyl-lysine.
1 B2RWS6 (/ISS)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 Q92793 (/TAS)
Protein-DNA complex assembly GO:0065004
The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.
1 B2RWS6 (/ISO)
Response to interleukin-1 GO:0070555
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
1 Q6JHU9 (/IEP)
Response to dexamethasone GO:0071548
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
1 B2RWS6 (/ISO)
Regulation of tubulin deacetylation GO:0090043
Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
1 Q09472 (/IDA)
Regulation of tubulin deacetylation GO:0090043
Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
1 B2RWS6 (/ISO)
Regulation of tubulin deacetylation GO:0090043
Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
1 B2RWS6 (/ISS)
Cellular response to virus GO:0098586
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
1 P45481 (/IMP)
Peptidyl-lysine crotonylation GO:0140066
The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid.
1 Q09472 (/IDA)
Peptidyl-lysine crotonylation GO:0140066
The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid.
1 B2RWS6 (/ISO)
Peptidyl-lysine crotonylation GO:0140066
The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid.
1 B2RWS6 (/ISS)
Peptidyl-lysine butyrylation GO:0140067
The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid.
1 B2RWS6 (/ISO)
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
1 Q6JHU9 (/IMP)
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
1 P45481 (/ISO)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
1 Q09472 (/IDA)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
1 Q6JHU9 (/IMP)
Regulation of signal transduction by p53 class mediator GO:1901796
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
1 Q09472 (/TAS)
Positive regulation of protein acetylation GO:1901985
Any process that activates or increases the frequency, rate or extent of protein acetylation.
1 B2RWS6 (/ISO)
Positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding GO:1905636
Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
1 Q09472 (/IDA)
Positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding GO:1905636
Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
1 B2RWS6 (/ISO)
Negative regulation of miRNA metabolic process GO:2000629
Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.
1 B2RWS6 (/ISO)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 A0A0R4INM9 (/IDA) A0A0R4IPF2 (/IDA) A0A2R8Q4T2 (/IDA) E1B8D6 (/IDA) P34545 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q6JHU9 (/IDA) Q92793 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 A0A0G2QC09 (/TAS) B2RWS6 (/TAS) P45481 (/TAS) Q09472 (/TAS) Q6JHU9 (/TAS) Q92793 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 A0A0R4INM9 (/IDA) A0A0R4IPF2 (/IDA) A0A2R8Q4T2 (/IDA) P34545 (/IDA) Q92793 (/IDA)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
3 B2RWS6 (/IDA) P45481 (/IDA) Q6JHU9 (/IDA)
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
2 B2RWS6 (/IDA) P45481 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
2 P45481 (/IDA) Q92793 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 B2RWS6 (/ISO) P45481 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q09472 (/IDA) Q92793 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 B2RWS6 (/ISO) P45481 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 B2RWS6 (/ISO) P45481 (/ISO)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
2 Q6JHU9 (/IDA) Q92793 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 B2RWS6 (/IDA) Q6JHU9 (/IDA)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
1 B2RWS6 (/ISO)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 P45481 (/ISO)
Condensed chromosome outer kinetochore GO:0000940
The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
1 P45481 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q92793 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 B2RWS6 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q92793 (/TAS)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 P45481 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q92793 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q09472 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 B2RWS6 (/ISO)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 P45481 (/ISO)
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
1 P45481 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 P45481 (/IMP)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 P45481 (/ISO)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
1 A0A0G2QC09 (/IPI)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
1 B2RWS6 (/ISO)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
1 Q09472 (/ISS)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
1 P45481 (/IDA)