The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P1 Nuclease
".
FunFam 2: Endonuclease 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Single-stranded DNA endodeoxyribonuclease activity GO:0000014
Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.
|
6 | F4JJL0 (/IDA) F4JJL3 (/IDA) Q8LDW6 (/IDA) Q9C9G4 (/IDA) Q9SXA6 (/IDA) Q9SXA6 (/IDA) |
|
Endonuclease activity GO:0004519
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
|
6 | F4JJL0 (/IDA) F4JJL3 (/IDA) Q8LDW6 (/IDA) Q9C9G4 (/IDA) Q9SXA6 (/IDA) Q9SXA6 (/IDA) |
|
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
|
6 | F4JJL0 (/IDA) F4JJL3 (/IDA) Q8LDW6 (/IDA) Q9C9G4 (/IDA) Q9SXA6 (/IDA) Q9SXA6 (/IDA) |
|
T/G mismatch-specific endonuclease activity GO:0043765
Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.
|
4 | F4JJL3 (/IDA) Q9C9G4 (/IDA) Q9SXA6 (/IDA) Q9SXA6 (/IDA) |
|
Double-stranded DNA exodeoxyribonuclease activity GO:0008309
Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule.
|
3 | Q9C9G4 (/IDA) Q9SXA6 (/IDA) Q9SXA6 (/IDA) |
|
Endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891
Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
|
2 | Q9SXA6 (/IDA) Q9SXA6 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA phosphodiester bond hydrolysis, endonucleolytic GO:0090502
The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
|
6 | F4JJL0 (/IDA) F4JJL3 (/IDA) Q8LDW6 (/IDA) Q9C9G4 (/IDA) Q9SXA6 (/IDA) Q9SXA6 (/IDA) |
|
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
|
2 | Q9SXA6 (/IEP) Q9SXA6 (/IEP) |
|
Floral organ senescence GO:0080187
An organ senescence that has as a participant a floral organ.
|
2 | Q9SXA6 (/IEP) Q9SXA6 (/IEP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.