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CATH Superfamily 1.10.510.40

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: IucA/IucC family siderophore biosynthesis protein

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Staphyloferrin B synthase. [EC: 6.3.2.56]
ATP + 2-((L-alanin-3-ylcarbamoyl)methyl)-3-(2-aminoethylcarbamoyl)-2- hydroxypropanoate + 2-oxoglutarate = AMP + diphosphate + staphyloferrin B.
  • Requires Mg(2+).
  • The enzyme, characterized from the bacterium Staphylococcus aureus, catalyzes the last step in the biosynthesis of the siderophore staphyloferrin B.
  • It belongs to a class of siderophore synthases known as type B nonribosomal peptide synthase-independent synthases (NIS).
  • Type B NIS enzymes recognize the delta-acid group of 2-oxoglutarate.
  • The enzyme forms a 2-oxoglutarate adenylate intermediate prior to ligation.
 36 A0A0H2X061 A0A0H2X061 A0A0H2X061 A0A0H2X061 A0A0H2X061 A0A0H2X061 A0A0H2XF13 A0A0H2XF13 A0A0H2XF13 A0A0H2XF13
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