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CATH Superfamily 1.10.510.40

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Siderophore biosynthesis protein, IucA/IucC family

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-2,3-diaminopropanoate--citrate ligase. [EC: 6.3.2.54]
ATP + L-2,3-diaminopropanoate + citrate = AMP + diphosphate + 2-((L-alanin-3-ylcarbamoyl)methyl)-2-hydroxybutanedioate.
  • Requires Mg(2+).
  • The enzyme, characterized from the bacterium Staphylococcus aureus, is involved in the biosynthesis of the siderophore staphyloferrin B.
  • It belongs to a class of siderophore synthases known as type A nonribosomal peptide synthase-independent synthases (NIS).
  • Type A NIS enzymes are responsible for the formation of amide or ester bonds between polyamines or amino alcohols and a prochiral carboxyl group of citrate.
  • The enzyme forms a citrate adenylate intermediate prior to ligation.
 49 A0A0H2WZX1 A0A0H2WZX1 A0A0H2WZX1 A0A0H2WZX1 A0A0H2WZX1 A0A0H2WZX1 A0A0H2WZX1 A0A0H2XIH1 A0A0H2XIH1 A0A0H2XIH1
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