View in Gene3D

CATH Superfamily 1.10.510.10

Transferase(Phosphotransferase) domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 399: Tyrosine-protein kinase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Non-specific protein-tyrosine kinase. [EC: 2.7.10.2]
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
  • Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain.
  • In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families.
  • Formerly EC 2.7.1.112.
 32 B3NC61 B3NC61 B3NC61 B3NC61 B3NC61 B4HU86 B4HU86 B4HU86 B4HU86 B4HU86
(22 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...