The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Hydantoin permease
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Uracil permease, putative

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Uracil:cation symporter activity GO:0015505
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).
5 P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA)
Allantoin:proton symporter activity GO:0005274
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.
2 Q04895 (/IMP) Q04895 (/IMP)
Nucleobase transmembrane transporter activity GO:0015205
Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.
2 Q9LZD0 (/IDA) Q9LZD0 (/IDA)
Uracil:cation symporter activity GO:0015505
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).
2 O14035 (/ISO) Q10279 (/ISO)
Uracil transmembrane transporter activity GO:0015210
Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.
1 Q10279 (/IMP)
Uridine transmembrane transporter activity GO:0015213
Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.
1 P38196 (/IDA)
Uridine transmembrane transporter activity GO:0015213
Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.
1 P38196 (/IMP)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Uracil transport GO:0015857
The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
5 P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA)
Allantoin catabolic process GO:0000256
The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
2 Q04895 (/IMP) Q04895 (/IMP)
Allantoin transport GO:0015720
The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q04895 (/IMP) Q04895 (/IMP)
Pyrimidine nucleobase salvage GO:0043100
Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.
2 Q9LZD0 (/IMP) Q9LZD0 (/IMP)
Uridine transport GO:0015862
The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P38196 (/IDA)
Uridine transport GO:0015862
The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P38196 (/IMP)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
1 P38196 (/IMP)
Uracil import across plasma membrane GO:0098721
The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.
1 Q10279 (/IGI)
Uracil import across plasma membrane GO:0098721
The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.
1 Q10279 (/IMP)
Uracil import across plasma membrane GO:0098721
The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.
1 O14035 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
8 P05316 (/HDA) P05316 (/HDA) P05316 (/HDA) P05316 (/HDA) P05316 (/HDA) P38196 (/HDA) Q04895 (/HDA) Q04895 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P38196 (/IDA) Q10279 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
6 P05316 (/HDA) P05316 (/HDA) P05316 (/HDA) P05316 (/HDA) P05316 (/HDA) P38196 (/HDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
5 P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA) P05316 (/IDA)
Plastid envelope GO:0009526
The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 Q9LZD0 (/IDA) Q9LZD0 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q10279 (/IDA)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
1 Q10279 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q10279 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q10279 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P38196 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P38196 (/IMP)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O14035 (/ISO)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 Q10279 (/ISO)