The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
GI Alpha 1, domain 2-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Guanine nucleotide-binding protein alpha-1 subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Olfactory receptor binding GO:0031849
Interacting selectively and non-covalently with an olfactory receptor.
2 P28052 (/IPI) Q18434 (/IPI)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P22454 (/IGI) P28052 (/IGI)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P22454 (/IMP) P28052 (/IMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
2 P22454 (/IGI) P28052 (/IGI)
G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium GO:1903554
Any G protein-coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium.
2 P22454 (/IGI) P28052 (/IGI)
G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium GO:1903554
Any G protein-coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium.
2 P22454 (/IMP) P28052 (/IMP)
Age-dependent response to oxidative stress GO:0001306
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism.
1 P28052 (/IMP)
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
1 Q18434 (/IGI)
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
1 Q18434 (/IMP)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
1 P28052 (/IGI)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 P28052 (/IGI)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 P28052 (/IMP)
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
1 P22454 (/IGI)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P28052 (/IGI)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P28052 (/IMP)
Dauer larval development GO:0040024
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 P28052 (/IMP)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q18434 (/IGI)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q18434 (/IMP)
Sensory perception of bitter taste GO:0050913
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 P28052 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
1 Q18434 (/IMP)
Cellular response to cGMP GO:0071321
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.
1 P28052 (/IMP)
Response to odorant GO:1990834
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.
1 Q18434 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 P22454 (/IDA) P28052 (/IDA) Q18434 (/IDA)
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
3 P22454 (/IDA) P28052 (/IDA) Q18434 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
2 P22454 (/IDA) P28052 (/IDA)
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