The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Neutral Protease Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1004 - - 86.9
2
472
3D
6g8bA03 - 83.7
3
4
423
3D
6endA03 - 96.9
4
334 - - 80.8
12
295
3D
6fzxA02 - 85.1
5
251 - - 76.9
7
178
3D
3qnfC02 - 76.6
6
162
3D
3q7jB02 - 85.5
8
140 - - 84.9
9
4
119
3D
2xq0A03 - 89.1
10
115
3D
5mj6B02 - 71.1
11
101 - - 95.5
13
84 - - 92.7
14
76 - - 84.3
15
58 - - 74.7
16
49
3D
4kxdA02 - 92.2
17
38 - - 46.4
21
33
3D
5y3iA03 - 0.7
18
32 - - 75.1
19
29
3D
4wz9B02 - 90.3
20
22 - - 36.4
22
17 - - 55.7
23
16 - - 24.2
24
15 - - 38.2
25
14 - - 66.2
26
11 - - 10.1
27
10 - - 10.1
28
10 - - 33.4
29
9 - - 5.9
31
9 - - 19.8
30
9 - - 67.6
32
9 - - 88.1
33
8 - - 93.4
36
7 - - 16.1
37
TBP TAF2
7 - - 6.6
35
7 - - 10.5
34
7 - - 1.9
39
6 - - 18.7
38
6 - - 11.5
40
5 - - 30.7
41
5 - - 3.2
43
5 - - 48.6
44
5 - - 80.9
42
5 - - 11.4
45
5 - - 66.4
48
4 - - 62.7
49
4 - - 46.7
46
4 - - 15.2
47
4 - - 13.2
50
3 - - 70.2
51
3 - - 8.8
52
3 - - 8.2
53
3 - - 13.7
61
2 - - 1.2
55
2 - - 37.1
68
2 - - 0.0
60
2 - - 5.1
69
2 - - 36.6
63
2 - - 32.1
62
2 - - 0.0
56
2 - - 13.1
70
2 - - 39.2
71
2 - - 27.7
58
2 - - 1.0
57
2 - - 1.5
64
2 - - 31.8
65
2 - - 25.2
66
2 - - 0.0
59
2 - - 3.3
72
2 - - 39.4
67
2 - - 6.8
54
2 - - 11.2
78
1 - - 0.0
112
1 - - 0.0
89
1 - - 0.0
91
1 - - 0.0
80
1 - - 0.0
92
1 - - 0.0
105
1 - - 0.0
111
1 - - 0.0
113
1 - - 0.0
82
1 - - 0.0
99
1 - - 0.0
90
1 - - 0.0
81
1 - - 0.0
76
1 - - 0.0
110
1 - - 0.0
102
1 - - 0.0
84
1 - - 0.0
77
1 - - 0.0
100
1 - - 0.0
79
1 - - 0.0
93
1 - - 0.0
103
1 - - 0.0
83
1 - - 0.0
101
1 - - 0.0
96
1 - - 0.0
116
1 - - 0.0
108
1 - - 0.0
85
1 - - 0.0
74
1 - - 0.0
117
1 - - 0.0
94
1 - - 0.0
109
1 - - 0.0
95
1 - - 0.0
106
1 - - 0.0
86
1 - - 0.0
75
1 - - 0.0
98
1 - - 0.0
107
1 - - 0.0
87
1 - - 0.0
115
1 - - 0.0
114
1 - - 0.0
73
1 - - 0.0
104
1 - - 0.0
97
1 - - 0.0
88
1 - - 0.0
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