The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Methyl-accepting chemotaxis protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Methyl-accepting chemotaxis sensory transducer

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
169 Q8E837 (/ISS) Q8E8U9 (/ISS) Q8E928 (/ISS) Q8E939 (/ISS) Q8EA56 (/ISS) Q8EAL2 (/ISS) Q8EB90 (/ISS) Q8EBE2 (/ISS) Q8EBU5 (/ISS) Q8EC62 (/ISS)
(159 more)
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
67 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP)
(57 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
61 P02942 (/IPI) P02942 (/IPI) P02942 (/IPI) P02942 (/IPI) P02942 (/IPI) P05704 (/IPI) P05704 (/IPI) P05704 (/IPI) P05704 (/IPI) P05704 (/IPI)
(51 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
61 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP)
(51 more)
Protein histidine kinase binding GO:0043424
Interacting selectively and non-covalently with protein histidine kinase.
43 P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA)
(33 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
38 P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA)
(28 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
20 P50466 (/IPI) P50466 (/IPI) P50466 (/IPI) P50466 (/IPI) P50466 (/IPI) P50466 (/IPI) P50466 (/IPI) P50466 (/IPI) P50466 (/IPI) P50466 (/IPI)
(10 more)
Amino acid binding GO:0016597
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
9 G3XD24 (/IDA) G3XD24 (/IDA) G3XD24 (/IDA) G3XD24 (/IDA) Q9HW91 (/IDA) Q9HW91 (/IDA) Q9HW91 (/IDA) Q9HW93 (/IDA) Q9HW93 (/IDA)
Transporter activity GO:0005215
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
6 P15492 (/ISS) P15492 (/ISS) P15492 (/ISS) P15492 (/ISS) P15492 (/ISS) P15492 (/ISS)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
169 Q8E837 (/ISS) Q8E8U9 (/ISS) Q8E928 (/ISS) Q8E939 (/ISS) Q8EA56 (/ISS) Q8EAL2 (/ISS) Q8EB90 (/ISS) Q8EBE2 (/ISS) Q8EBU5 (/ISS) Q8EC62 (/ISS)
(159 more)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
78 G3XD24 (/IMP) G3XD24 (/IMP) G3XD24 (/IMP) G3XD24 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P05704 (/IMP)
(68 more)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
43 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP)
(33 more)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
43 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP)
(33 more)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
43 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP)
(33 more)
Signal complex assembly GO:0007172
The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.
38 P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA)
(28 more)
Detection of chemical stimulus GO:0009593
The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.
38 P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA)
(28 more)
Regulation of chemotaxis GO:0050920
Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
38 P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA)
(28 more)
Positive regulation of post-translational protein modification GO:1901875
Any process that activates or increases the frequency, rate or extent of post-translational protein modification.
38 P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP) P07017 (/IMP)
(28 more)
Positive aerotaxis GO:0052131
The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.
28 P50466 (/IMP) P50466 (/IMP) P50466 (/IMP) P50466 (/IMP) P50466 (/IMP) P50466 (/IMP) P50466 (/IMP) P50466 (/IMP) P50466 (/IMP) P50466 (/IMP)
(18 more)
Response to amino acid GO:0043200
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
14 G3XD24 (/IMP) G3XD24 (/IMP) G3XD24 (/IMP) G3XD24 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) Q9HW91 (/IMP)
(4 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
10 P15492 (/ISS) P15492 (/ISS) P15492 (/ISS) P15492 (/ISS) P15492 (/ISS) P15492 (/ISS) Q9KTQ7 (/ISS) Q9KTQ7 (/ISS) Q9KTQ7 (/ISS) Q9KTQ7 (/ISS)
Aerotaxis GO:0009454
The directed movement of a motile cell or organism in response to environmental oxygen.
8 Q9I3F6 (/IMP) Q9I3F6 (/IMP) Q9I3F6 (/IMP) Q9I3F6 (/IMP) Q9I3F6 (/IMP) Q9I3F6 (/IMP) Q9I3F6 (/IMP) Q9I3F6 (/IMP)
Signal complex assembly GO:0007172
The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.
5 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP)
Detection of chemical stimulus GO:0009593
The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.
5 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP)
Regulation of protein histidine kinase activity GO:0032110
Any process that modulates the frequency, rate or extent of protein histidine kinase activity.
5 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP)
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
5 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP)
Cell motility GO:0048870
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
5 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP)
Regulation of chemotaxis GO:0050920
Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
5 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP)
Regulation of bacterial-type flagellum-dependent cell motility GO:1902021
Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.
5 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP)
Aerotaxis GO:0009454
The directed movement of a motile cell or organism in response to environmental oxygen.
4 Q884S4 (/ISS) Q884S4 (/ISS) Q884S4 (/ISS) Q884S4 (/ISS)
Positive chemotaxis GO:0050918
The directed movement of a motile cell or organism towards a higher concentration of a chemical.
2 Q9I0I6 (/IMP) Q9I0I6 (/IMP)
Cellular response to organic substance GO:0071310
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
2 Q9I0I6 (/IMP) Q9I0I6 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
67 P02942 (/RCA) P02942 (/RCA) P02942 (/RCA) P02942 (/RCA) P02942 (/RCA) P05704 (/RCA) P05704 (/RCA) P05704 (/RCA) P05704 (/RCA) P05704 (/RCA)
(57 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
61 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP)
(51 more)
Methyl accepting chemotaxis protein complex GO:0098561
A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.
61 P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P02942 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP) P05704 (/IMP)
(51 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
49 P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P05704 (/IDA) P05704 (/IDA) P05704 (/IDA) P05704 (/IDA) P05704 (/IDA)
(39 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
43 P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P02942 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA)
(33 more)
Methyl accepting chemotaxis protein complex GO:0098561
A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.
38 P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA) P07017 (/IDA)
(28 more)