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CATH Superfamily 1.10.287.470

Helix hairpin bin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Helix hairpin bin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Efflux RND transporter periplasmic adaptor subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 73 P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI)
(63 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 73 P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI)
(63 more)
Xenobiotic transmembrane transporter activity GO:0042910
Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
 73 P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP)
(63 more)
Xenobiotic transmembrane transporter activity GO:0042910
Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
 6 G3XD25 (/IDA) G3XD25 (/IDA) G3XD25 (/IDA) Q51395 (/IDA) Q51395 (/IDA) Q51395 (/IDA)
Xenobiotic transmembrane transporter activity GO:0042910
Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
 3 Q749P5 (/ISS) Q8E8H1 (/ISS) Q8ECN4 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
 79 P24180 (/ISS) P24180 (/ISS) P24180 (/ISS) P24180 (/ISS) P24180 (/ISS) P24180 (/ISS) P24180 (/ISS) P24180 (/ISS) P24180 (/ISS) P24180 (/ISS)
(69 more)
Drug transmembrane transport GO:0006855
The process in which a drug is transported across a membrane.
 73 P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP)
(63 more)
Bile acid and bile salt transport GO:0015721
The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 73 P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP) P0AE06 (/IMP)
(63 more)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
 6 Q9KLV2 (/ISS) Q9KLV2 (/ISS) Q9KLV2 (/ISS) Q9KLV2 (/ISS) Q9KLV2 (/ISS) Q9KLV2 (/ISS)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
 6 G3XD25 (/EXP) G3XD25 (/EXP) G3XD25 (/EXP) Q51395 (/EXP) Q51395 (/EXP) Q51395 (/EXP)
Drug transmembrane transport GO:0006855
The process in which a drug is transported across a membrane.
 3 Q749P5 (/ISS) Q8E8H1 (/ISS) Q8ECN4 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 149 P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA)
(139 more)
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
 76 P24180 (/IMP) P24180 (/IMP) P24180 (/IMP) P24180 (/IMP) P24180 (/IMP) P24180 (/IMP) P24180 (/IMP) P24180 (/IMP) P24180 (/IMP) P24180 (/IMP)
(66 more)
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
 73 P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA) P0AE06 (/IDA)
(63 more)
Efflux pump complex GO:1990281
A protein complex that is capable of efflux transmembrane transporter activity.
 73 P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI) P0AE06 (/IPI)
(63 more)