CATH Superfamily 1.10.287.2720
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: Oxysterol-binding protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
4 | Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9H0X9 (/IDA) |
Phospholipid transporter activity GO:0005548
Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.
|
4 | Q9BZF1 (/TAS) Q9BZF1 (/TAS) Q9BZF1 (/TAS) Q9H0X9 (/TAS) |
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
4 | Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9H0X9 (/IDA) |
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
4 | Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9H0X9 (/IDA) |
Phosphatidylserine transfer activity GO:0140343
Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.
|
4 | Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9H0X9 (/IDA) |
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
2 | B9EJ86 (/ISO) Q9ER64 (/ISO) |
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
2 | B9EJ86 (/ISS) Q9ER64 (/ISS) |
Phospholipid transporter activity GO:0005548
Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.
|
2 | B9EJ86 (/ISO) Q9ER64 (/ISO) |
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
2 | B9EJ86 (/ISO) Q9ER64 (/ISO) |
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
2 | B9EJ86 (/ISO) Q9ER64 (/ISO) |
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
2 | B9EJ86 (/ISS) Q9ER64 (/ISS) |
Phosphatidylserine transfer activity GO:0140343
Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.
|
2 | B9EJ86 (/ISS) Q9ER64 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | B9EJ86 (/IPI) |
Oxysterol binding GO:0008142
Interacting selectively and non-covalently with oxysterol, an oxidized form of cholesterol.
|
1 | Q9H0X9 (/NAS) |
There are 23 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
|
4 | Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9H0X9 (/IDA) |
Phosphatidylserine acyl-chain remodeling GO:0036150
Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.
|
4 | Q9BZF1 (/TAS) Q9BZF1 (/TAS) Q9BZF1 (/TAS) Q9H0X9 (/TAS) |
Negative regulation of sequestering of triglyceride GO:0010891
Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
|
3 | Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9BZF1 (/IDA) |
Activation of protein kinase B activity GO:0032148
Any process that initiates the activity of the inactive enzyme protein kinase B.
|
3 | Q9BZF1 (/ISS) Q9BZF1 (/ISS) Q9BZF1 (/ISS) |
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
3 | Q9BZF1 (/IDA) Q9BZF1 (/IDA) Q9BZF1 (/IDA) |
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
|
3 | Q9BZF1 (/ISS) Q9BZF1 (/ISS) Q9BZF1 (/ISS) |
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
3 | Q9BZF1 (/ISS) Q9BZF1 (/ISS) Q9BZF1 (/ISS) |
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | G5EC19 (/IMP) Q8MPR9 (/IMP) |
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
|
2 | B9EJ86 (/ISO) Q9ER64 (/ISO) |
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
|
2 | B9EJ86 (/ISS) Q9ER64 (/ISS) |
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
|
2 | G5EC19 (/IMP) Q8MPR9 (/IMP) |
Golgi to plasma membrane transport GO:0006893
The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
|
1 | Q9H0X9 (/NAS) |
Cholesterol metabolic process GO:0008203
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
|
1 | Q9H0X9 (/NAS) |
Negative regulation of sequestering of triglyceride GO:0010891
Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
|
1 | B9EJ86 (/ISO) |
Cholesterol transport GO:0030301
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9H0X9 (/NAS) |
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | B9EJ86 (/IMP) |
Activation of protein kinase B activity GO:0032148
Any process that initiates the activity of the inactive enzyme protein kinase B.
|
1 | B9EJ86 (/IMP) |
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
1 | B9EJ86 (/ISO) |
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
|
1 | B9EJ86 (/IMP) |
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
|
1 | B9EJ86 (/IDA) |
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
|
1 | B9EJ86 (/IMP) |
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | B9EJ86 (/IMP) |
Protein localization to nuclear pore GO:0090204
A process in which a protein is transported to, or maintained in, a nuclear pore.
|
1 | B9EJ86 (/IMP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | Q9BZF1 (/TAS) Q9BZF1 (/TAS) Q9BZF1 (/TAS) Q9H0X9 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
4 | Q9BZF1 (/HDA) Q9BZF1 (/HDA) Q9BZF1 (/HDA) Q9H0X9 (/HDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | B9EJ86 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9H0X9 (/NAS) |
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | B9EJ86 (/IMP) |
Cortical endoplasmic reticulum GO:0032541
A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
|
1 | B9EJ86 (/ISO) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q9H0X9 (/IDA) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q9ER64 (/ISO) |
Endoplasmic reticulum-plasma membrane contact site GO:0140268
A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.
|
1 | Q9H0X9 (/IDA) |
Endoplasmic reticulum-plasma membrane contact site GO:0140268
A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.
|
1 | Q9ER64 (/ISO) |
Endoplasmic reticulum-plasma membrane contact site GO:0140268
A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.
|
1 | Q9ER64 (/ISS) |