The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28: Dynamin associated protein 160, isoform A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 M9ND00 (/IPI) M9PBF6 (/IPI) M9PDC7 (/IPI) O61618 (/IPI) O61639 (/IPI) Q1WWC9 (/IPI) Q8INU2 (/IPI) Q9VIF7 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of neuroblast proliferation GO:0002052
Any process that activates or increases the rate of neuroblast proliferation.
8 M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) O61618 (/IMP) O61639 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q9VIF7 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
8 M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) O61618 (/IMP) O61639 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q9VIF7 (/IMP)
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
8 M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) O61618 (/IDA) O61639 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q9VIF7 (/IDA)
Synaptic vesicle endocytosis GO:0048488
A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.
8 M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) O61618 (/IMP) O61639 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q9VIF7 (/IMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 M9ND00 (/IMP)
Clathrin-dependent synaptic vesicle endocytosis GO:0150007
Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds.
1 M9ND00 (/IMP)
Bulk synaptic vesicle endocytosis GO:0150008
Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.
1 M9ND00 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) O61618 (/IDA) O61639 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q9VIF7 (/IDA)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
8 M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) O61618 (/IDA) O61639 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q9VIF7 (/IDA)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
8 M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) O61618 (/IDA) O61639 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q9VIF7 (/IDA)
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