The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 79: Calcium and integrin-binding family member 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 27 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
22 |
A0PJX0 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
O75838 (/IPI)
(12 more) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
18 |
A0PJX0 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
(8 more) |
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
16 |
A0PJX0 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
(6 more) |
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
15 |
C7A276 (/ISS)
C7A278 (/ISS)
C7A278 (/ISS)
C7A278 (/ISS)
Q0P523 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
(5 more) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
15 |
C7A276 (/ISS)
C7A278 (/ISS)
C7A278 (/ISS)
C7A278 (/ISS)
Q0P523 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
Q568Z7 (/ISS)
(5 more) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
14 |
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
(4 more) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
10 | C7A276 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q9Z309 (/ISS) Q9Z309 (/ISS) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
5 | Q0P523 (/ISO) Q9D9N5 (/ISO) Q9Z0F4 (/ISO) Q9Z309 (/ISO) Q9Z309 (/ISO) |
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
4 | Q0P523 (/ISO) Q9D9N5 (/ISO) Q9Z309 (/ISO) Q9Z309 (/ISO) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Calcium-dependent protein kinase inhibitor activity GO:0008427
Stops, prevents or reduces the activity of a calcium-dependent protein kinase.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Ras GTPase binding GO:0017016
Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
|
4 | Q99828 (/IPI) Q99828 (/IPI) Q99828 (/IPI) Q99828 (/IPI) |
Protein serine/threonine kinase inhibitor activity GO:0030291
Stops, prevents or reduces the activity of a protein serine/threonine kinase.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Protein membrane anchor GO:0043495
Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
|
4 | Q99828 (/IGI) Q99828 (/IGI) Q99828 (/IGI) Q99828 (/IGI) |
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
2 | Q9Z309 (/IPI) Q9Z309 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q9Z309 (/ISO) Q9Z309 (/ISO) |
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
2 | Q9Z309 (/IDA) Q9Z309 (/IDA) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | Q9R010 (/IPI) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | Q9Z0F4 (/ISO) |
Calcium-dependent protein kinase inhibitor activity GO:0008427
Stops, prevents or reduces the activity of a calcium-dependent protein kinase.
|
1 | Q9Z0F4 (/ISO) |
Ras GTPase binding GO:0017016
Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
|
1 | Q9Z0F4 (/ISO) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9R010 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9Z0F4 (/ISO) |
Protein serine/threonine kinase inhibitor activity GO:0030291
Stops, prevents or reduces the activity of a protein serine/threonine kinase.
|
1 | Q9Z0F4 (/ISO) |
Protein membrane anchor GO:0043495
Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
|
1 | Q9Z0F4 (/IMP) |
Protein membrane anchor GO:0043495
Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
|
1 | Q9Z0F4 (/ISO) |
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
1 | Q9Z0F4 (/IPI) |
There are 107 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
|
21 |
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
(11 more) |
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
|
21 |
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
(11 more) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
14 |
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
(4 more) |
Cellular response to ATP GO:0071318
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
|
14 |
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
(4 more) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
10 | C7A276 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q9Z309 (/ISS) Q9Z309 (/ISS) |
Cellular response to ATP GO:0071318
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
|
10 | C7A276 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q9Z309 (/ISS) Q9Z309 (/ISS) |
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Response to ischemia GO:0002931
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Thrombopoietin-mediated signaling pathway GO:0038163
A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Negative regulation of megakaryocyte differentiation GO:0045653
Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of protein serine/threonine kinase activity GO:0071902
Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of cell migration involved in sprouting angiogenesis GO:0090050
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Positive regulation of male germ cell proliferation GO:2000256
Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.
|
8 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q99828 (/ISS) Q9R010 (/ISS) |
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
|
7 | Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) Q9Z309 (/IMP) Q9Z309 (/IMP) |
Negative regulation of microtubule depolymerization GO:0007026
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Endomitotic cell cycle GO:0007113
A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
|
5 | Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) Q9W2Q5 (/IMP) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Negative regulation of neuron projection development GO:0010977
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
5 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q9Z0F4 (/IMP) |
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Double-strand break repair GO:0006302
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
|
4 | Q99828 (/TAS) Q99828 (/TAS) Q99828 (/TAS) Q99828 (/TAS) |
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Negative regulation of microtubule depolymerization GO:0007026
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Endomitotic cell cycle GO:0007113
A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
4 | Q99828 (/TAS) Q99828 (/TAS) Q99828 (/TAS) Q99828 (/TAS) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Negative regulation of neuron projection development GO:0010977
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
4 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) |
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Positive regulation of calcineurin-NFAT signaling cascade GO:0070886
Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Extrinsic apoptotic signaling pathway GO:0097191
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
|
4 | Q99828 (/TAS) Q99828 (/TAS) Q99828 (/TAS) Q99828 (/TAS) |
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Positive regulation of protein localization to plasma membrane GO:1903078
Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
|
4 | Q99828 (/IGI) Q99828 (/IGI) Q99828 (/IGI) Q99828 (/IGI) |
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
2 | Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
2 | Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
2 | Q9Z309 (/ISO) Q9Z309 (/ISO) |
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
|
2 | Q9Z309 (/IDA) Q9Z309 (/IDA) |
Positive regulation of calcineurin-NFAT signaling cascade GO:0070886
Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
|
2 | Q9R010 (/IMP) Q9Z0F4 (/IMP) |
Cellular response to ATP GO:0071318
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
|
2 | Q9Z309 (/ISO) Q9Z309 (/ISO) |
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
1 | Q9Z0F4 (/IMP) |
Response to ischemia GO:0002931
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
|
1 | Q9Z0F4 (/IDA) |
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
1 | Q9Z0F4 (/ISO) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | Q9Z0F4 (/ISO) |
Negative regulation of microtubule depolymerization GO:0007026
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
|
1 | Q9Z0F4 (/ISO) |
Endomitotic cell cycle GO:0007113
A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
|
1 | Q9Z0F4 (/ISO) |
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
|
1 | Q9Z0F4 (/IMP) |
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
|
1 | Q6PC72 (/IMP) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q9Z0F4 (/IMP) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q9Z0F4 (/ISO) |
Negative regulation of neuron projection development GO:0010977
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q9Z0F4 (/ISO) |
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
1 | Q9Z0F4 (/IMP) |
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
|
1 | Q9Z0F4 (/ISO) |
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
|
1 | Q9Z0F4 (/ISO) |
Thrombopoietin-mediated signaling pathway GO:0038163
A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q9Z0F4 (/IMP) |
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
1 | Q9Z0F4 (/ISO) |
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
|
1 | Q6PC72 (/IMP) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9Z0F4 (/ISO) |
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
|
1 | Q9Z0F4 (/IMP) |
Negative regulation of megakaryocyte differentiation GO:0045653
Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
|
1 | Q9Z0F4 (/IMP) |
Neuromast development GO:0048884
The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.
|
1 | Q6PC72 (/IMP) |
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
1 | Q9Z0F4 (/ISO) |
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
|
1 | Q9Z0F4 (/ISO) |
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of calcineurin-NFAT signaling cascade GO:0070886
Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
|
1 | Q9Z0F4 (/ISO) |
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
1 | Q9Z0F4 (/ISO) |
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | Q9Z0F4 (/IDA) |
Positive regulation of protein serine/threonine kinase activity GO:0071902
Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of cell migration involved in sprouting angiogenesis GO:0090050
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
1 | Q9Z0F4 (/ISO) |
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
1 | Q9Z0F4 (/ISO) |
Positive regulation of protein localization to plasma membrane GO:1903078
Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
|
1 | Q9Z0F4 (/IMP) |
Positive regulation of protein localization to plasma membrane GO:1903078
Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
|
1 | Q9Z0F4 (/ISO) |
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
|
1 | Q9Z0F4 (/ISO) |
Positive regulation of male germ cell proliferation GO:2000256
Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.
|
1 | Q9Z0F4 (/IMP) |
There are 66 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
26 |
C7A276 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
(16 more) |
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
|
22 |
C7A276 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
(12 more) |
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
|
22 |
C7A276 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
O75838 (/ISS)
(12 more) |
Stereocilium GO:0032420
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
|
16 |
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
(6 more) |
Cuticular plate GO:0032437
A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
|
14 |
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
O75838 (/IDA)
(4 more) |
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
|
14 |
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
O75838 (/HDA)
(4 more) |
Stereocilium GO:0032420
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
|
10 | C7A276 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q9Z309 (/ISS) Q9Z309 (/ISS) |
Cuticular plate GO:0032437
A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
|
10 | C7A276 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q568Z7 (/ISS) Q9Z309 (/ISS) Q9Z309 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
8 | A0A140VK09 (/IDA) A0A140VK09 (/IDA) A0A140VK09 (/IDA) A0A140VK09 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q9R010 (/IDA) Q9Z0F4 (/IDA) Q9Z309 (/IDA) Q9Z309 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
8 | A0A140VK09 (/IDA) A0A140VK09 (/IDA) A0A140VK09 (/IDA) A0A140VK09 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
|
7 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q9Z0F4 (/IDA) Q9Z309 (/IDA) Q9Z309 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q9R010 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q9Z0F4 (/IMP) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Calcineurin complex GO:0005955
A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.
|
5 | Q9W2Q5 (/ISS) Q9W2Q5 (/ISS) Q9W2Q5 (/ISS) Q9W2Q5 (/ISS) Q9W2Q5 (/ISS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
5 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q9Z0F4 (/IDA) |
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
5 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q9R010 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
|
5 | Q17QE5 (/ISS) Q17QE5 (/ISS) Q17QE5 (/ISS) Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
4 | Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) Q99828 (/IMP) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
|
4 | Q99828 (/HDA) Q99828 (/HDA) Q99828 (/HDA) Q99828 (/HDA) |
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
4 | Q99828 (/HDA) Q99828 (/HDA) Q99828 (/HDA) Q99828 (/HDA) |
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
|
4 | Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) Q99828 (/IDA) |
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
|
2 | Q9Z309 (/IDA) Q9Z309 (/IDA) |
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
|
2 | Q9Z309 (/IDA) Q9Z309 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | Q9R010 (/ISS) Q9Z0F4 (/ISS) |
Muscle tendon junction GO:0005927
A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.
|
2 | Q9Z309 (/IDA) Q9Z309 (/IDA) |
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
|
2 | Q9Z309 (/IDA) Q9Z309 (/IDA) |
Stereocilium GO:0032420
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
|
2 | Q9Z309 (/ISO) Q9Z309 (/ISO) |
Cuticular plate GO:0032437
A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
|
2 | Q9Z309 (/ISO) Q9Z309 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9Z0F4 (/ISO) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9Z0F4 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9Z0F4 (/ISO) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
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1 | Q9Z0F4 (/ISO) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
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1 | Q9Z0F4 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
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1 | Q9Z0F4 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
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1 | Q9Z0F4 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
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1 | Q9R010 (/ISS) |
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
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1 | Q9Z0F4 (/ISO) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
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1 | Q9R010 (/IDA) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
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1 | Q9Z0F4 (/ISO) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
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1 | Q9R010 (/IDA) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
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1 | Q9Z0F4 (/ISO) |
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
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1 | Q9Z0F4 (/ISO) |
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
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1 | Q9Z0F4 (/ISO) |
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
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1 | Q9Z0F4 (/ISO) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
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1 | Q9Z0F4 (/ISO) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
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1 | Q9Z0F4 (/ISO) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
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1 | Q9Z0F4 (/ISO) |
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
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1 | Q9Z0F4 (/ISO) |