The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 401: Troponin C 25D

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
7 G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS)
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
7 G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS) G5EF37 (/ISS)
Troponin I binding GO:0031013
Interacting selectively and non-covalently with troponin I, the inhibitory subunit of the troponin complex.
7 G5EF37 (/IPI) G5EF37 (/IPI) G5EF37 (/IPI) G5EF37 (/IPI) G5EF37 (/IPI) G5EF37 (/IPI) G5EF37 (/IPI)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
7 G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
7 G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP)
Skeletal muscle thin filament assembly GO:0030240
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.
7 G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP) G5EF37 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Contractile fiber GO:0043292
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
7 G5EF37 (/IDA) G5EF37 (/IDA) G5EF37 (/IDA) G5EF37 (/IDA) G5EF37 (/IDA) G5EF37 (/IDA) G5EF37 (/IDA)
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