The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 290: LETM1 and EF-hand domain-containing protein 1, mit...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Calcium:proton antiporter activity GO:0015369
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).
|
3 | Q0VA06 (/ISS) Q0VCA3 (/ISS) Q1LY46 (/ISS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | O95202 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O95202 (/IPI) |
|
Calcium:proton antiporter activity GO:0015369
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).
|
1 | O95202 (/IDA) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein hexamerization GO:0034214
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
|
4 | O95202 (/ISS) Q0VA06 (/ISS) Q0VCA3 (/ISS) Q1LY46 (/ISS) |
|
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
4 | O95202 (/ISS) Q0VA06 (/ISS) Q0VCA3 (/ISS) Q1LY46 (/ISS) |
|
Mitochondrial calcium ion transmembrane transport GO:0006851
The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
|
3 | Q0VA06 (/ISS) Q0VCA3 (/ISS) Q1LY46 (/ISS) |
|
Mitochondrial calcium ion homeostasis GO:0051560
Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.
|
3 | Q0VA06 (/ISS) Q0VCA3 (/ISS) Q1LY46 (/ISS) |
|
Calcium export from the mitochondrion GO:0099093
A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol.
|
3 | Q0VA06 (/ISS) Q0VCA3 (/ISS) Q1LY46 (/ISS) |
|
Mitochondrial calcium ion transmembrane transport GO:0006851
The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
|
1 | O95202 (/IDA) |
|
Cristae formation GO:0042407
The assembly of cristae, the inwards folds of the inner mitochondrial membrane.
|
1 | O95202 (/IMP) |
|
Mitochondrial calcium ion homeostasis GO:0051560
Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.
|
1 | O95202 (/IDA) |
|
Negative regulation of mitochondrial calcium ion concentration GO:0051562
Any process that decreases the concentration of calcium ions in mitochondria.
|
1 | O95202 (/IMP) |
|
Negative regulation of mitochondrial calcium ion concentration GO:0051562
Any process that decreases the concentration of calcium ions in mitochondria.
|
1 | Q0VCA3 (/ISS) |
|
Calcium export from the mitochondrion GO:0099093
A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol.
|
1 | O95202 (/IDA) |
|
Regulation of cellular hyperosmotic salinity response GO:1900069
Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.
|
1 | O95202 (/IMP) |
|
Regulation of cellular hyperosmotic salinity response GO:1900069
Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.
|
1 | Q0VCA3 (/ISS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
3 | Q0VA06 (/ISS) Q0VCA3 (/ISS) Q1LY46 (/ISS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O95202 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O95202 (/TAS) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | O95202 (/IDA) |
