The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 261: Uncharacterized protein, isoform B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
5 E3CTP7 (/NAS) Q8MMD2 (/NAS) Q8MMD3 (/NAS) Q8WQ61 (/NAS) Q9W111 (/NAS)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
5 E3CTP7 (/IMP) Q8MMD2 (/IMP) Q8MMD3 (/IMP) Q8WQ61 (/IMP) Q9W111 (/IMP)
Synaptic vesicle endocytosis GO:0048488
A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.
5 E3CTP7 (/IDA) Q8MMD2 (/IDA) Q8MMD3 (/IDA) Q8WQ61 (/IDA) Q9W111 (/IDA)
Synaptic vesicle endocytosis GO:0048488
A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.
5 E3CTP7 (/IMP) Q8MMD2 (/IMP) Q8MMD3 (/IMP) Q8WQ61 (/IMP) Q9W111 (/IMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q9W111 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 E3CTP7 (/HDA) Q8MMD2 (/HDA) Q8MMD3 (/HDA) Q8WQ61 (/HDA) Q9W111 (/HDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
5 E3CTP7 (/IDA) Q8MMD2 (/IDA) Q8MMD3 (/IDA) Q8WQ61 (/IDA) Q9W111 (/IDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
5 E3CTP7 (/IMP) Q8MMD2 (/IMP) Q8MMD3 (/IMP) Q8WQ61 (/IMP) Q9W111 (/IMP)
Extrinsic component of presynaptic endocytic zone membrane GO:0098894
The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
5 E3CTP7 (/IDA) Q8MMD2 (/IDA) Q8MMD3 (/IDA) Q8WQ61 (/IDA) Q9W111 (/IDA)
Presynaptic endocytic zone cytoplasmic component GO:0098834
The cytoplasmic component of the presynaptic endocytic zone.
1 E3CTP7 (/IDA)
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