The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24: 1-phosphatidylinositol 4,5-bisphosphate phosphodie...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylinositol phospholipase C activity GO:0004435
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
13 A0A096NTF5 (/ISS) A0A2J8QDF6 (/ISS) A0A2J8QDF6 (/ISS) E2RT75 (/ISS) F7D8C0 (/ISS) F7I202 (/ISS) F7I4D1 (/ISS) G3QEQ0 (/ISS) H0X1B8 (/ISS) H9YV70 (/ISS)
(3 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 A2AT91 (/IPI) P13217 (/IPI) P13217 (/IPI) Q00722 (/IPI) Q15147 (/IPI) Q5FWA6 (/IPI) Q6P8L2 (/IPI) Q91UZ1 (/IPI) V9GXQ9 (/IPI)
Mitogen-activated protein kinase binding GO:0051019
Interacting selectively and non-covalently with a mitogen-activated protein kinase.
5 A2AT91 (/ISO) Q5FWA6 (/ISO) Q6P8L2 (/ISO) Q91UZ1 (/ISO) V9GXQ9 (/ISO)
Phosphatidylinositol phospholipase C activity GO:0004435
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
4 O89040 (/IMP) P13217 (/IMP) P13217 (/IMP) Q00722 (/IMP)
Phospholipase C activity GO:0004629
Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
4 P13217 (/TAS) P13217 (/TAS) Q00722 (/TAS) Q15147 (/TAS)
Phosphatidylinositol phospholipase C activity GO:0004435
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
3 P13217 (/TAS) P13217 (/TAS) Q00722 (/TAS)
Phosphatidylinositol phospholipase C activity GO:0004435
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
2 G1MWY7 (/IDA) Q91086 (/IDA)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
2 P13217 (/NAS) P13217 (/NAS)
Phosphatidylinositol phospholipase C activity GO:0004435
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
1 A3KGF7 (/ISO)
Phospholipase C activity GO:0004629
Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
1 O89040 (/IMP)
Phospholipase C activity GO:0004629
Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
1 A3KGF7 (/ISO)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
1 O89040 (/IDA)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
1 A3KGF7 (/ISO)
G-protein beta/gamma-subunit complex binding GO:0031683
Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits.
1 O89040 (/IDA)
G-protein beta/gamma-subunit complex binding GO:0031683
Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits.
1 A3KGF7 (/ISO)
Mitogen-activated protein kinase binding GO:0051019
Interacting selectively and non-covalently with a mitogen-activated protein kinase.
1 Q9QW07 (/IPI)

There are 49 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of potassium ion transport GO:0043267
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 A2AT91 (/ISO) Q5FWA6 (/ISO) Q6P8L2 (/ISO) Q91UZ1 (/ISO) V9GXQ9 (/ISO)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
5 A2AT91 (/IMP) Q5FWA6 (/IMP) Q6P8L2 (/IMP) Q91UZ1 (/IMP) V9GXQ9 (/IMP)
Detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580
The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.
3 O89040 (/IMP) P13217 (/IMP) P13217 (/IMP)
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
3 P13217 (/TAS) P13217 (/TAS) Q00722 (/TAS)
Entrainment of circadian clock by photoperiod GO:0043153
The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).
3 P13217 (/IGI) P13217 (/IGI) P25455 (/IGI)
Mucosal immune response GO:0002385
An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.
2 P13217 (/IMP) P13217 (/IMP)
Diacylglycerol biosynthetic process GO:0006651
The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
2 P13217 (/TAS) P13217 (/TAS)
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
2 Q00722 (/TAS) Q15147 (/TAS)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
2 P13217 (/IMP) P13217 (/IMP)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
2 P13217 (/TAS) P13217 (/TAS)
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
2 P13217 (/IMP) P13217 (/IMP)
Light-induced release of internally sequestered calcium ion GO:0008377
The process in which the detection of light triggers the release of internally sequestered calcium ions.
2 P13217 (/TAS) P13217 (/TAS)
Phospholipid biosynthetic process GO:0008654
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
2 P13217 (/TAS) P13217 (/TAS)
Entrainment of circadian clock GO:0009649
The synchronization of a circadian rhythm to environmental time cues such as light.
2 P13217 (/IMP) P13217 (/IMP)
Rhodopsin mediated signaling pathway GO:0016056
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
2 P13217 (/IMP) P13217 (/IMP)
Deactivation of rhodopsin mediated signaling GO:0016059
The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).
2 P13217 (/IDA) P13217 (/IDA)
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
2 P13217 (/TAS) P13217 (/TAS)
Thermotaxis GO:0043052
The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
2 P13217 (/IMP) P13217 (/IMP)
Inositol phosphate metabolic process GO:0043647
The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
2 Q00722 (/TAS) Q15147 (/TAS)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
2 P13217 (/IMP) P13217 (/IMP)
Phosphatidylinositol metabolic process GO:0046488
The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
2 P13217 (/IMP) P13217 (/IMP)
Negative regulation of compound eye retinal cell programmed cell death GO:0046673
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
2 P13217 (/IMP) P13217 (/IMP)
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway GO:0051482
Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G protein-coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol.
2 P13217 (/TAS) P13217 (/TAS)
Cellular response to light stimulus GO:0071482
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 P13217 (/IMP) P13217 (/IMP)
Positive regulation of clathrin-dependent endocytosis GO:2000370
Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
2 P13217 (/IMP) P13217 (/IMP)
Detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580
The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.
1 O89040 (/IDA)
Detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580
The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.
1 A3KGF7 (/ISO)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 G5EBH0 (/IGI)
Phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
1 O89040 (/IDA)
Phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
1 A3KGF7 (/ISO)
Activation of phospholipase C activity GO:0007202
The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.
1 Q00722 (/TAS)
Dopamine receptor signaling pathway GO:0007212
The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
1 G5EBH0 (/IMP)
Wnt signaling pathway, calcium modulating pathway GO:0007223
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
1 Q00722 (/TAS)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
1 Q9QW07 (/NAS)
Flight behavior GO:0007629
The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.
1 P25455 (/IGI)
Positive regulation of acetylcholine secretion, neurotransmission GO:0014057
Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.
1 G5EBH0 (/IMP)
Protein localization to synapse GO:0035418
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
1 G5EBH0 (/IGI)
Regulation of locomotion GO:0040012
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
1 G5EBH0 (/IGI)
Positive regulation of locomotion GO:0040017
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
1 G5EBH0 (/IMP)
Regulation of pharyngeal pumping GO:0043051
Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.
1 G5EBH0 (/IGI)
Regulation of pharyngeal pumping GO:0043051
Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.
1 G5EBH0 (/IMP)
Thermotaxis GO:0043052
The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
1 G5EBH0 (/IGI)
Negative regulation of potassium ion transport GO:0043267
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9QW07 (/IMP)
Regulation of oviposition GO:0046662
Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
1 G5EBH0 (/IMP)
Positive regulation of axon regeneration GO:0048680
Any process that activates, maintains or increases the rate of axon regeneration.
1 G5EBH0 (/IMP)
Sensory perception of bitter taste GO:0050913
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 A3KGF7 (/IMP)
Neuron cellular homeostasis GO:0070050
The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.
1 P25455 (/IGI)
Regulation of neuromuscular synaptic transmission GO:1900073
Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.
1 P25455 (/IGI)

There are 23 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 A2AT91 (/ISO) Q5FWA6 (/ISO) Q6P8L2 (/ISO) Q91UZ1 (/ISO) V9GXQ9 (/ISO)
Smooth endoplasmic reticulum GO:0005790
The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Parallel fiber to Purkinje cell synapse GO:0098688
An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Parallel fiber to Purkinje cell synapse GO:0098688
An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.
5 A2AT91 (/IMP) Q5FWA6 (/IMP) Q6P8L2 (/IMP) Q91UZ1 (/IMP) V9GXQ9 (/IMP)
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
5 A2AT91 (/IDA) Q5FWA6 (/IDA) Q6P8L2 (/IDA) Q91UZ1 (/IDA) V9GXQ9 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
5 A2AT91 (/IMP) Q5FWA6 (/IMP) Q6P8L2 (/IMP) Q91UZ1 (/IMP) V9GXQ9 (/IMP)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 G1MWY7 (/IDA) O89040 (/IDA) Q91086 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 A3KGF7 (/IDA) Q9QW07 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q00722 (/TAS) Q15147 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 G5EBH0 (/IDA) O89040 (/IDA)
InaD signaling complex GO:0016027
A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.
2 P13217 (/IPI) P13217 (/IPI)
InaD signaling complex GO:0016027
A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.
2 P13217 (/TAS) P13217 (/TAS)
Rhabdomere GO:0016028
The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.
2 P13217 (/IDA) P13217 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 O89040 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 A3KGF7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 A3KGF7 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 A3KGF7 (/ISO)
G-protein beta/gamma-subunit complex GO:0031680
The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.
1 O89040 (/IDA)
G-protein beta/gamma-subunit complex GO:0031680
The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.
1 A3KGF7 (/ISO)
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