The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 180: Calcium-dependent protein kinase 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
12 Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA)
(2 more)
Calcium-dependent protein serine/threonine phosphatase activity GO:0004723
Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.
12 Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA)
(2 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
12 Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA)
(2 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
5 P62344 (/ISS) P62344 (/ISS) P62344 (/ISS) P62344 (/ISS) P62344 (/ISS)
Calcium-dependent protein serine/threonine kinase activity GO:0009931
Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions.
5 P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
17 P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA) Q8IBS5 (/IDA)
(7 more)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
5 P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA) P62344 (/IDA)
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