The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 139: Peflin isoform 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | Q5PQ53 (/IPI) Q5PQ53 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) |
|
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
5 | Q5PQ53 (/ISS) Q5PQ53 (/ISS) Q641Z8 (/ISS) Q6DC93 (/ISS) Q8BFY6 (/ISS) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
4 | Q9UBV8 (/HDA) Q9UBV8 (/HDA) Q9UBV8 (/HDA) Q9UBV8 (/HDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
4 | Q9UBV8 (/TAS) Q9UBV8 (/TAS) Q9UBV8 (/TAS) Q9UBV8 (/TAS) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
4 | Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) |
|
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
4 | Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) |
|
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
4 | Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) |
|
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
4 | Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q8BFY6 (/ISO) |
|
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | Q8BFY6 (/ISO) |
|
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
1 | Q8BFY6 (/ISO) |
|
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | Q8BFY6 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
5 | Q5PQ53 (/ISS) Q5PQ53 (/ISS) Q641Z8 (/ISS) Q6DC93 (/ISS) Q8BFY6 (/ISS) |
|
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
5 | Q5PQ53 (/ISS) Q5PQ53 (/ISS) Q641Z8 (/ISS) Q6DC93 (/ISS) Q8BFY6 (/ISS) |
|
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
5 | Q5PQ53 (/ISS) Q5PQ53 (/ISS) Q641Z8 (/ISS) Q6DC93 (/ISS) Q8BFY6 (/ISS) |
|
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
5 | Q5PQ53 (/ISS) Q5PQ53 (/ISS) Q641Z8 (/ISS) Q6DC93 (/ISS) Q8BFY6 (/ISS) |
|
Positive regulation of protein monoubiquitination GO:1902527
Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
|
5 | Q5PQ53 (/ISS) Q5PQ53 (/ISS) Q641Z8 (/ISS) Q6DC93 (/ISS) Q8BFY6 (/ISS) |
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
4 | Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) |
|
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
4 | Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) |
|
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
4 | Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) |
|
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
4 | Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) |
|
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
4 | Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) Q9UBV8 (/IPI) |
|
Positive regulation of protein monoubiquitination GO:1902527
Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
|
4 | Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) Q9UBV8 (/IMP) |
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
1 | Q8BFY6 (/ISO) |
|
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
1 | Q8BFY6 (/ISO) |
|
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
1 | Q8BFY6 (/ISO) |
|
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
1 | Q8BFY6 (/ISO) |
|
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q8BFY6 (/ISO) |
|
Positive regulation of protein monoubiquitination GO:1902527
Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
|
1 | Q8BFY6 (/ISO) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
5 | Q5PQ53 (/ISS) Q5PQ53 (/ISS) Q641Z8 (/ISS) Q6DC93 (/ISS) Q8BFY6 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q9UBV8 (/IDA) Q9UBV8 (/IDA) Q9UBV8 (/IDA) Q9UBV8 (/IDA) |
|
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
4 | Q9UBV8 (/IDA) Q9UBV8 (/IDA) Q9UBV8 (/IDA) Q9UBV8 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
4 | Q9UBV8 (/HDA) Q9UBV8 (/HDA) Q9UBV8 (/HDA) Q9UBV8 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8BFY6 (/ISO) |
|
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
1 | Q8BFY6 (/ISO) |
