The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Glutamate cysteine ligase subdomain
".
FunFam 1: Glutamate--cysteine ligase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glutamate-cysteine ligase activity GO:0004357
Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate.
|
6 | P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) |
|
Glutamate-cysteine ligase activity GO:0004357
Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate.
|
6 | P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glutathione biosynthetic process GO:0006750
The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
|
7 | P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) Q6FLG3 (/IMP) |
|
Glutathione biosynthetic process GO:0006750
The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
|
6 | P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) |
|
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
6 | P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) P32477 (/IMP) |
|
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
6 | P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) |
|
Detoxification of cadmium ion GO:0071585
Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
|
1 | Q6FLG3 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
6 | P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) P32477 (/IDA) |