The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"C-terminal domain of DFF45/ICAD (DFF-C domain)
".
FunFam 1: DNA fragmentation factor subunit alpha
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O00273 (/IPI) O54786 (/IPI) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | O00273 (/IPI) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | O54786 (/ISO) |
|
Protein folding chaperone GO:0044183
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
|
1 | O00273 (/IPI) |
|
Protein folding chaperone GO:0044183
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
|
1 | O54786 (/ISO) |
|
Deoxyribonuclease inhibitor activity GO:0060703
Stops, prevents or reduces the activity of deoxyribonuclease.
|
1 | O00273 (/IMP) |
|
Deoxyribonuclease inhibitor activity GO:0060703
Stops, prevents or reduces the activity of deoxyribonuclease.
|
1 | O54786 (/ISO) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Apoptotic DNA fragmentation GO:0006309
The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
|
1 | O00273 (/TAS) |
|
Negative regulation of deoxyribonuclease activity GO:0032076
Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
|
1 | O00273 (/IMP) |
|
Negative regulation of deoxyribonuclease activity GO:0032076
Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
|
1 | O54786 (/ISO) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | O54786 (/IMP) |
|
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
|
1 | O00273 (/IMP) |
|
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
|
1 | O54786 (/ISO) |
|
Thymocyte apoptotic process GO:0070242
Any apoptotic process in a thymocyte, an immature T cell located in the thymus.
|
1 | O54786 (/IMP) |
|
Negative regulation of execution phase of apoptosis GO:1900118
Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.
|
1 | O00273 (/IDA) |
|
Negative regulation of execution phase of apoptosis GO:1900118
Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.
|
1 | O54786 (/ISO) |
|
Negative regulation of apoptotic DNA fragmentation GO:1902511
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.
|
1 | O00273 (/IDA) |
|
Negative regulation of apoptotic DNA fragmentation GO:1902511
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.
|
1 | O54786 (/IMP) |
|
Negative regulation of apoptotic DNA fragmentation GO:1902511
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.
|
1 | O54786 (/ISO) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | A0A0G2JY18 (/IDA) O00273 (/IDA) Q498U6 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | A0A024R4H5 (/IDA) O00273 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | A0A024R4H5 (/IDA) O00273 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | O00273 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | O54786 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O54786 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | O00273 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O54786 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O00273 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O54786 (/ISO) |
