The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Tetraspanin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24: Tetraspanin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P19397 (/IPI) P19397 (/IPI) P19397 (/IPI) P19397 (/IPI) P19397 (/IPI)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of myoblast fusion GO:1901741
Any process that activates or increases the frequency, rate or extent of myoblast fusion.
8 P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P24485 (/ISS) Q58DM3 (/ISS) Q58DM3 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
5 P19397 (/NAS) P19397 (/NAS) P19397 (/NAS) P19397 (/NAS) P19397 (/NAS)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
5 P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS)
Positive regulation of myoblast fusion GO:1901741
Any process that activates or increases the frequency, rate or extent of myoblast fusion.
3 Q61451 (/IDA) Q61451 (/IDA) Q61451 (/IDA)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
1 P24485 (/NAS)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P24485 (/ISS) Q58DM3 (/ISS) Q58DM3 (/ISS)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
8 P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P19397 (/ISS) P24485 (/ISS) Q58DM3 (/ISS) Q58DM3 (/ISS)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
5 P19397 (/IDA) P19397 (/IDA) P19397 (/IDA) P19397 (/IDA) P19397 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS)
Specific granule membrane GO:0035579
The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
5 P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P19397 (/HDA) P19397 (/HDA) P19397 (/HDA) P19397 (/HDA) P19397 (/HDA)
Tertiary granule membrane GO:0070821
The lipid bilayer surrounding a tertiary granule.
5 P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS) P19397 (/TAS)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
3 Q61451 (/ISO) Q61451 (/ISO) Q61451 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q61451 (/IDA) Q61451 (/IDA) Q61451 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
3 Q61451 (/IDA) Q61451 (/IDA) Q61451 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
3 Q61451 (/ISO) Q61451 (/ISO) Q61451 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P24485 (/IDA)
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