The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Tetraspanin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 10: Tetraspanin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P35762 (/IPI) P35762 (/IPI) P60033 (/IPI) P60033 (/IPI) P60033 (/IPI) P60033 (/IPI) P60033 (/IPI) Q62745 (/IPI)
Virus receptor activity GO:0001618
Combining with a virus component and mediating entry of the virus into the cell.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
MHC class II protein complex binding GO:0023026
Interacting selectively and non-covalently with the class II major histocompatibility complex.
5 P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA)
MHC class II protein binding GO:0042289
Interacting selectively and non-covalently with major histocompatibility complex class II molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Transferrin receptor binding GO:1990459
Interacting selectively and non-covalently with the transferrin receptor.
5 P60033 (/IPI) P60033 (/IPI) P60033 (/IPI) P60033 (/IPI) P60033 (/IPI)
Virus receptor activity GO:0001618
Combining with a virus component and mediating entry of the virus into the cell.
2 P35762 (/ISO) P35762 (/ISO)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
2 P35762 (/ISO) P35762 (/ISO)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
2 P35762 (/ISO) P35762 (/ISO)
MHC class II protein binding GO:0042289
Interacting selectively and non-covalently with major histocompatibility complex class II molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
2 P35762 (/ISO) P35762 (/ISO)
Transferrin receptor binding GO:1990459
Interacting selectively and non-covalently with the transferrin receptor.
2 P35762 (/ISO) P35762 (/ISO)

There are 93 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of inflammatory response to antigenic stimulus GO:0002863
Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60033 (/ISS) P60033 (/ISS) P60033 (/ISS)
(10 more)
Myoblast fusion involved in skeletal muscle regeneration GO:0014905
A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60033 (/ISS) P60033 (/ISS) P60033 (/ISS)
(10 more)
Receptor internalization GO:0031623
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60033 (/ISS) P60033 (/ISS) P60033 (/ISS)
(10 more)
Positive regulation of B cell receptor signaling pathway GO:0050861
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60033 (/ISS) P60033 (/ISS) P60033 (/ISS)
(10 more)
Cellular response to low-density lipoprotein particle stimulus GO:0071404
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60033 (/ISS) P60033 (/ISS) P60033 (/ISS)
(10 more)
Osteoclast fusion GO:0072675
The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60033 (/ISS) P60033 (/ISS) P60033 (/ISS)
(10 more)
Regulation of macrophage migration GO:1905521
Any process that modulates the frequency, rate or extent of macrophage migration.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60033 (/ISS) P60033 (/ISS) P60033 (/ISS)
(10 more)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
19 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(9 more)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
19 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(9 more)
Positive regulation of 1-phosphatidylinositol 4-kinase activity GO:0043128
Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase.
19 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(9 more)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
19 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(9 more)
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Humoral immune response mediated by circulating immunoglobulin GO:0002455
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60034 (/ISS) P60034 (/ISS) P60034 (/ISS)
(7 more)
CD4-positive, alpha-beta T cell costimulation GO:0035783
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Positive regulation of T cell receptor signaling pathway GO:0050862
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Positive regulation of protein exit from endoplasmic reticulum GO:0070863
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Positive regulation of receptor clustering GO:1903911
Any process that activates or increases the frequency, rate or extent of receptor clustering.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Positive regulation of T-helper 2 cell cytokine production GO:2000553
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Positive regulation of CD4-positive, alpha-beta T cell proliferation GO:2000563
Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:2001190
Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Macrophage fusion GO:0034238
The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
15 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60034 (/ISS) P60034 (/ISS) P60034 (/ISS)
(5 more)
Positive regulation of B cell activation GO:0050871
Any process that activates or increases the frequency, rate or extent of B cell activation.
15 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60034 (/ISS) P60034 (/ISS) P60034 (/ISS)
(5 more)
Positive regulation of B cell receptor signaling pathway GO:0050861
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
7 P35762 (/IMP) P35762 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Humoral immune response mediated by circulating immunoglobulin GO:0002455
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Regulation of complement activation GO:0030449
Any process that modulates the frequency, rate or extent of complement activation.
5 P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Macrophage fusion GO:0034238
The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
CD4-positive, alpha-beta T cell costimulation GO:0035783
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Positive regulation of 1-phosphatidylinositol 4-kinase activity GO:0043128
Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
5 P60033 (/IGI) P60033 (/IGI) P60033 (/IGI) P60033 (/IGI) P60033 (/IGI)
Viral entry into host cell GO:0046718
The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
5 P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS)
Receptor-mediated virion attachment to host cell GO:0046813
The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.
5 P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
5 P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS)
Positive regulation of T cell receptor signaling pathway GO:0050862
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Positive regulation of protein exit from endoplasmic reticulum GO:0070863
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Positive regulation of receptor clustering GO:1903911
Any process that activates or increases the frequency, rate or extent of receptor clustering.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Positive regulation of protein catabolic process in the vacuole GO:1904352
Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Positive regulation of adaptive immune memory response GO:1905676
Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.
5 P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP) P60033 (/IMP)
Positive regulation of T-helper 2 cell cytokine production GO:2000553
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Positive regulation of CD4-positive, alpha-beta T cell proliferation GO:2000563
Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:2001190
Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
2 P35762 (/ISO) P35762 (/ISO)
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
2 P35762 (/ISO) P35762 (/ISO)
Humoral immune response mediated by circulating immunoglobulin GO:0002455
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of inflammatory response to antigenic stimulus GO:0002863
Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2 P35762 (/IMP) P35762 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 P35762 (/ISO) P35762 (/ISO)
Myoblast fusion involved in skeletal muscle regeneration GO:0014905
A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2 P35762 (/IMP) P35762 (/IMP)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
2 P35762 (/TAS) P35762 (/TAS)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
2 P35762 (/TAS) P35762 (/TAS)
Receptor internalization GO:0031623
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
2 P35762 (/IDA) P35762 (/IDA)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
2 P35762 (/ISO) P35762 (/ISO)
Macrophage fusion GO:0034238
The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
2 P35762 (/IMP) P35762 (/IMP)
Macrophage fusion GO:0034238
The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
2 P35762 (/ISO) P35762 (/ISO)
CD4-positive, alpha-beta T cell costimulation GO:0035783
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.
2 P35762 (/ISO) P35762 (/ISO)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of 1-phosphatidylinositol 4-kinase activity GO:0043128
Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of B cell receptor signaling pathway GO:0050861
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of T cell receptor signaling pathway GO:0050862
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of B cell activation GO:0050871
Any process that activates or increases the frequency, rate or extent of B cell activation.
2 P35762 (/IMP) P35762 (/IMP)
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of protein exit from endoplasmic reticulum GO:0070863
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
2 P35762 (/ISO) P35762 (/ISO)
Cellular response to low-density lipoprotein particle stimulus GO:0071404
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.
2 P35762 (/IDA) P35762 (/IDA)
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
2 P35762 (/ISO) P35762 (/ISO)
Osteoclast fusion GO:0072675
The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.
2 P35762 (/IMP) P35762 (/IMP)
Positive regulation of receptor clustering GO:1903911
Any process that activates or increases the frequency, rate or extent of receptor clustering.
2 P35762 (/IMP) P35762 (/IMP)
Positive regulation of receptor clustering GO:1903911
Any process that activates or increases the frequency, rate or extent of receptor clustering.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of protein catabolic process in the vacuole GO:1904352
Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.
2 P35762 (/ISO) P35762 (/ISO)
Regulation of macrophage migration GO:1905521
Any process that modulates the frequency, rate or extent of macrophage migration.
2 P35762 (/IDA) P35762 (/IDA)
Positive regulation of adaptive immune memory response GO:1905676
Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.
2 P35762 (/ISO) P35762 (/ISO)
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
2 P35762 (/IGI) P35762 (/IGI)
Positive regulation of T-helper 2 cell cytokine production GO:2000553
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.
2 P35762 (/IMP) P35762 (/IMP)
Positive regulation of T-helper 2 cell cytokine production GO:2000553
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of CD4-positive, alpha-beta T cell proliferation GO:2000563
Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
2 P35762 (/ISO) P35762 (/ISO)
Positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:2001190
Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
2 P35762 (/IMP) P35762 (/IMP)
Positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:2001190
Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
2 P35762 (/ISO) P35762 (/ISO)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 Q62745 (/IEP)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
1 Q62745 (/IEP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q62745 (/IDA)

There are 28 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
20 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(10 more)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Tetraspanin-enriched microdomain GO:0097197
A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.
17 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(7 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
16 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P35762 (/ISS) P35762 (/ISS) P60034 (/ISS)
(6 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
14 O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) O97703 (/ISS) P60034 (/ISS) P60034 (/ISS) P60034 (/ISS)
(4 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) Q62745 (/IDA)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS) P60033 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
5 P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA) P60033 (/HDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Tetraspanin-enriched microdomain GO:0097197
A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.
5 P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA) P60033 (/IDA)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
2 P35762 (/ISO) P35762 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P35762 (/ISO) P35762 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P35762 (/ISO) P35762 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P35762 (/IDA) P35762 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P35762 (/ISO) P35762 (/ISO)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
2 P35762 (/ISO) P35762 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 P35762 (/ISO) P35762 (/ISO)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
2 P35762 (/ISO) P35762 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P35762 (/ISO) P35762 (/ISO)
Tetraspanin-enriched microdomain GO:0097197
A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.
2 P35762 (/ISO) P35762 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 Q62745 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...