The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Insulin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Insulin-like growth factor II preproprotein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 18 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
21 P01346 (/ISS) P01346 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P09535 (/ISS) P10764 (/ISS) P10764 (/ISS) P23695 (/ISS) P23695 (/ISS)
(11 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P01344 (/IPI) P01344 (/IPI) P01344 (/IPI) P01346 (/IPI) P01346 (/IPI) P09535 (/IPI) Q08279 (/IPI)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
5 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA) Q90WW4 (/IDA) Q90WW4 (/IDA)
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
4 Q5U3B4 (/IDA) Q8JIE4 (/IDA) Q8UUI9 (/IDA) Q9PUD0 (/IDA)
Insulin receptor binding GO:0005158
Interacting selectively and non-covalently with the insulin receptor.
3 P01344 (/IPI) P01344 (/IPI) P01344 (/IPI)
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
3 P01344 (/IMP) P01344 (/IMP) P01344 (/IMP)
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
3 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA)
Protein serine/threonine kinase activator activity GO:0043539
Binds to and increases the activity of a protein serine/threonine kinase.
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
2 Q6INW9 (/ISS) Q6INW9 (/ISS)
Insulin receptor binding GO:0005158
Interacting selectively and non-covalently with the insulin receptor.
1 P09535 (/ISO)
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
1 P09535 (/IPI)
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
1 P09535 (/ISO)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
1 P09535 (/ISO)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
1 P09535 (/ISO)
Protein serine/threonine kinase activator activity GO:0043539
Binds to and increases the activity of a protein serine/threonine kinase.
1 P09535 (/IMP)
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
1 P09535 (/IMP)

There are 92 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
21 P01346 (/ISS) P01346 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P09535 (/ISS) P10764 (/ISS) P10764 (/ISS) P23695 (/ISS) P23695 (/ISS)
(11 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
16 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS) P01346 (/ISS) P01346 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P10764 (/ISS) P10764 (/ISS)
(6 more)
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
16 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS) P01346 (/ISS) P01346 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P10764 (/ISS) P10764 (/ISS)
(6 more)
Regulation of histone modification GO:0031056
Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.
16 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS) P01346 (/ISS) P01346 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P10764 (/ISS) P10764 (/ISS)
(6 more)
Regulation of muscle cell differentiation GO:0051147
Any process that modulates the frequency, rate or extent of muscle cell differentiation.
16 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS) P01346 (/ISS) P01346 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P10764 (/ISS) P10764 (/ISS)
(6 more)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
13 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P10764 (/ISS) P10764 (/ISS) P23695 (/ISS) P23695 (/ISS)
(3 more)
Embryonic placenta morphogenesis GO:0060669
The process in which the embryonic placenta is generated and organized.
13 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS) P07456 (/ISS) P07456 (/ISS) P07456 (/ISS) P10764 (/ISS) P10764 (/ISS) P23695 (/ISS) P23695 (/ISS)
(3 more)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
9 B8QGI3 (/IDA) B8QGI3 (/IDA) B8QGI3 (/IDA) I3PGL3 (/IDA) P07456 (/IDA) P07456 (/IDA) P07456 (/IDA) Q2F6J3 (/IDA) Q862G1 (/IDA)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
4 Q5U3B4 (/IGI) Q8JIE4 (/IGI) Q8UUI9 (/IGI) Q9PUD0 (/IGI)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
4 Q5U3B4 (/IMP) Q8JIE4 (/IMP) Q8UUI9 (/IMP) Q9PUD0 (/IMP)
Notochord development GO:0030903
The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
4 Q5U3B4 (/IGI) Q8JIE4 (/IGI) Q8UUI9 (/IGI) Q9PUD0 (/IGI)
Notochord development GO:0030903
The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
4 Q5U3B4 (/IMP) Q8JIE4 (/IMP) Q8UUI9 (/IMP) Q9PUD0 (/IMP)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
4 Q9MYX4 (/ISS) V9Q2R7 (/ISS) V9Q2R7 (/ISS) V9Q2R7 (/ISS)
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Regulation of gene expression by genetic imprinting GO:0006349
Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself.
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
3 P01344 (/NAS) P01344 (/NAS) P01344 (/NAS)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 P01344 (/IC) P01344 (/IC) P01344 (/IC)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Insulin receptor signaling pathway via phosphatidylinositol 3-kinase GO:0038028
The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Positive regulation of activated T cell proliferation GO:0042104
Any process that activates or increases the rate or extent of activated T cell proliferation.
3 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
3 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA)
Cellular protein metabolic process GO:0044267
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Positive regulation of glycogen biosynthetic process GO:0045725
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Positive regulation of mitotic nuclear division GO:0045840
Any process that activates or increases the frequency, rate or extent of mitosis.
3 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA)
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
3 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
3 P01344 (/IDA) P01344 (/IDA) P01344 (/IDA)
Positive regulation of glycogen (starch) synthase activity GO:2000467
Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.
3 P01344 (/ISS) P01344 (/ISS) P01344 (/ISS)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
2 Q90WW4 (/IDA) Q90WW4 (/IDA)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
2 Q6INW9 (/ISS) Q6INW9 (/ISS)
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
2 P01346 (/IEP) P01346 (/IEP)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
2 P01346 (/IMP) P01346 (/IMP)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
2 P01346 (/IEP) P01346 (/IEP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 P01346 (/IDA) P01346 (/IDA)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
2 P01346 (/IEP) P01346 (/IEP)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2 P01346 (/IEP) P01346 (/IEP)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
2 P01346 (/IDA) P01346 (/IDA)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
2 P01346 (/IEP) P01346 (/IEP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
2 P01346 (/IEP) P01346 (/IEP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 P01346 (/IDA) P01346 (/IDA)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
2 P01346 (/IGI) P01346 (/IGI)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
2 P01346 (/IEP) P01346 (/IEP)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
2 P01346 (/IGI) P01346 (/IGI)
Negative regulation of natural killer cell mediated cytotoxicity GO:0045953
Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
2 P01346 (/IDA) P01346 (/IDA)
Head morphogenesis GO:0060323
The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
2 Q90WW4 (/IDA) Q90WW4 (/IDA)
Head morphogenesis GO:0060323
The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
2 Q6INW9 (/ISS) Q6INW9 (/ISS)
Cellular response to mechanical stimulus GO:0071260
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
2 P01346 (/IEP) P01346 (/IEP)
Positive regulation of steroid hormone biosynthetic process GO:0090031
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
2 P01346 (/IDA) P01346 (/IDA)
Positive regulation of vascular endothelial cell proliferation GO:1905564
Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.
2 P01346 (/IGI) P01346 (/IGI)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 P09535 (/IMP)
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
1 P09535 (/IEP)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 P09535 (/IMP)
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
1 P09535 (/IMP)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
1 P09535 (/IMP)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
1 P09535 (/ISO)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P09535 (/ISO)
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 P09535 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P09535 (/ISO)
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
1 Q8JIE4 (/IMP)
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
1 P09535 (/IMP)
Regulation of histone modification GO:0031056
Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.
1 P09535 (/IMP)
Fin regeneration GO:0031101
The regrowth of fin tissue following its loss or destruction.
1 Q8JIE4 (/IMP)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
1 P09535 (/ISO)
Insulin receptor signaling pathway via phosphatidylinositol 3-kinase GO:0038028
The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.
1 P09535 (/IMP)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
1 P09535 (/IMP)
Positive regulation of activated T cell proliferation GO:0042104
Any process that activates or increases the rate or extent of activated T cell proliferation.
1 P09535 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P09535 (/ISO)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 A4GUE9 (/IDA)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
1 P09535 (/IMP)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
1 P09535 (/ISO)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
1 P09535 (/ISO)
Positive regulation of glycogen biosynthetic process GO:0045725
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
1 P09535 (/IMP)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
1 P09535 (/ISO)
Positive regulation of mitotic nuclear division GO:0045840
Any process that activates or increases the frequency, rate or extent of mitosis.
1 P09535 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P09535 (/IGI)
Negative regulation of natural killer cell mediated cytotoxicity GO:0045953
Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
1 P09535 (/ISO)
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
1 P09535 (/IMP)
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
1 P09535 (/ISO)
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
1 Q8JIE4 (/IMP)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
1 P09535 (/IMP)
Striated muscle cell differentiation GO:0051146
The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
1 P09535 (/IGI)
Regulation of muscle cell differentiation GO:0051147
Any process that modulates the frequency, rate or extent of muscle cell differentiation.
1 P09535 (/IMP)
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
1 P09535 (/ISO)
Embryonic placenta morphogenesis GO:0060669
The process in which the embryonic placenta is generated and organized.
1 P09535 (/IMP)
Positive regulation of steroid hormone biosynthetic process GO:0090031
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
1 P09535 (/ISO)
Positive regulation of vascular endothelial cell proliferation GO:1905564
Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.
1 P09535 (/ISO)
Positive regulation of glycogen (starch) synthase activity GO:2000467
Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.
1 P09535 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
19 A4GUE9 (/IDA) B8QGI3 (/IDA) B8QGI3 (/IDA) B8QGI3 (/IDA) F6KZW8 (/IDA) F6KZW8 (/IDA) I3PGL3 (/IDA) P01346 (/IDA) P01346 (/IDA) P07456 (/IDA)
(9 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 Q5U3B4 (/NAS) Q8UUI9 (/NAS) Q90WW4 (/NAS) Q90WW4 (/NAS) Q9PUD0 (/NAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q9MYX4 (/ISS) V9Q2R7 (/ISS) V9Q2R7 (/ISS) V9Q2R7 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Platelet alpha granule lumen GO:0031093
The volume enclosed by the membrane of the platelet alpha granule.
3 P01344 (/TAS) P01344 (/TAS) P01344 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P09535 (/ISO)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 P09535 (/HDA)