The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 885:
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
1 | Q9P6H9 (/IDA) |
|
Transcription termination site DNA binding GO:0001160
Interacting selectively and non-covalently with a region of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.
|
1 | Q9P6H9 (/IDA) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q9P6H9 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9P6H9 (/IPI) |
|
RDNA spacer replication fork barrier binding GO:0043110
Interacting selectively and non-covalently with replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription.
|
1 | Q9P6H9 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q9P6H9 (/IDA) |
|
RDNA spacer replication fork barrier binding, bending GO:0110035
The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
1 | Q9P6H9 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Termination of RNA polymerase I transcription GO:0006363
The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.
|
1 | Q9P6H9 (/IDA) |
|
Termination of RNA polymerase I transcription GO:0006363
The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.
|
1 | Q9P6H9 (/IMP) |
|
Replication fork arrest at rDNA repeats GO:0031582
A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.
|
1 | Q9P6H9 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation GO:0036278
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen.
|
1 | Q9P6H9 (/IMP) |
|
Replication fork arrest GO:0043111
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.
|
1 | Q9P6H9 (/IMP) |
|
Cis-acting DNA replication termination GO:0071946
A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.
|
1 | Q9P6H9 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RDNA heterochromatin GO:0033553
A region of heterochromatin located at the rDNA repeats in a chromosome.
|
1 | Q9P6H9 (/EXP) |
|
Nuclear rDNA heterochromatin GO:1902377
Any rDNA heterochromatin that is part of a nucleus.
|
1 | Q9P6H9 (/EXP) |