The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 50: LIM homeobox 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 Q68G74 (/IPI) Q68G74 (/IPI) Q68G74 (/IPI) Q68G74 (/IPI) Q68G74 (/IPI) Q9R1R0 (/IPI) Q9UPM6 (/IPI) Q9UPM6 (/IPI) Q9UPM6 (/IPI)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
8 Q68G74 (/ISA) Q68G74 (/ISA) Q68G74 (/ISA) Q68G74 (/ISA) Q68G74 (/ISA) Q9UPM6 (/ISA) Q9UPM6 (/ISA) Q9UPM6 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
8 Q68G74 (/ISM) Q68G74 (/ISM) Q68G74 (/ISM) Q68G74 (/ISM) Q68G74 (/ISM) Q9UPM6 (/ISM) Q9UPM6 (/ISM) Q9UPM6 (/ISM)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
4 Q9R1R0 (/NAS) Q9UPM6 (/NAS) Q9UPM6 (/NAS) Q9UPM6 (/NAS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 Q9UPM6 (/NAS) Q9UPM6 (/NAS) Q9UPM6 (/NAS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 A5PMV8 (/ISS) Q6BDC3 (/ISS)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cerebral cortex radially oriented cell migration GO:0021799
The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.
3 Q9UPM6 (/ISS) Q9UPM6 (/ISS) Q9UPM6 (/ISS)
Cerebral cortex tangential migration GO:0021800
The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.
3 Q9UPM6 (/ISS) Q9UPM6 (/ISS) Q9UPM6 (/ISS)
Cerebral cortex GABAergic interneuron migration GO:0021853
The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
3 Q9UPM6 (/ISS) Q9UPM6 (/ISS) Q9UPM6 (/ISS)
Cell maturation GO:0048469
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
3 Q9UPM6 (/ISS) Q9UPM6 (/ISS) Q9UPM6 (/ISS)
Forebrain neuron development GO:0021884
The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.
2 O35652 (/IGI) Q9R1R0 (/IGI)
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
1 O35652 (/IMP)
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
1 O35652 (/IMP)
Cerebral cortex radially oriented cell migration GO:0021799
The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.
1 Q9R1R0 (/IMP)
Cerebral cortex tangential migration GO:0021800
The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.
1 Q9R1R0 (/IMP)
Cerebral cortex GABAergic interneuron migration GO:0021853
The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
1 Q9R1R0 (/IMP)
Forebrain neuron fate commitment GO:0021877
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain.
1 Q9R1R0 (/IGI)
Forebrain neuron differentiation GO:0021879
The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.
1 O35652 (/IMP)
Cerebral cortex neuron differentiation GO:0021895
The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
1 Q9R1R0 (/IGI)
Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
1 O35652 (/IMP)
Cell maturation GO:0048469
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
1 Q9R1R0 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q9R1R0 (/IDA) Q9UPM6 (/IDA) Q9UPM6 (/IDA) Q9UPM6 (/IDA)
Female germ cell nucleus GO:0001674
The nucleus of the female germ cell, a reproductive cell in females.
1 O35652 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9R1R0 (/ISO)