The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42: Transcriptional activator Myb isoform A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 A0A2R8Q8E3 (/IPI) A0A2R8RYE8 (/IPI) F1QP24 (/IPI) F1QP25 (/IPI) P01103 (/IPI) P06876 (/IPI) P10242 (/IPI) P10242 (/IPI) Q6PBA4 (/IPI) Q9PTJ4 (/IPI)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
7 A0A2R8Q8E3 (/IDA) A0A2R8RYE8 (/IDA) F1QP24 (/IDA) F1QP25 (/IDA) P51960 (/IDA) Q6PBA4 (/IDA) Q9PTJ4 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
6 A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
4 P06876 (/IDA) P10242 (/IDA) P10242 (/IDA) P10243 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P10242 (/ISA) P10242 (/ISA) P10243 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P10242 (/ISM) P10242 (/ISM) P10243 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P10242 (/NAS) P10242 (/NAS) P10243 (/NAS)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
2 P06876 (/ISO) P51960 (/ISO)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P10242 (/IC) P10242 (/IC)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P06876 (/IDA) P10243 (/IDA)
Showing 1 to 10 of 16 entries

There are 55 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
6 A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP)
Hematopoietic stem cell migration GO:0035701
The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
6 A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
6 A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
6 A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP)
Regulation of neutrophil differentiation GO:0045658
Any process that modulates the frequency, rate or extent of neutrophil differentiation.
6 A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI)
Regulation of neutrophil differentiation GO:0045658
Any process that modulates the frequency, rate or extent of neutrophil differentiation.
6 A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP)
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
6 A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
6 A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
6 A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
5 P06876 (/IDA) P10242 (/IDA) P10242 (/IDA) P10243 (/IDA) P51960 (/IDA)
Showing 1 to 10 of 55 entries

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
6 A0A2R8Q8E3 (/IDA) A0A2R8RYE8 (/IDA) F1QP24 (/IDA) F1QP25 (/IDA) Q6PBA4 (/IDA) Q9PTJ4 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 P06876 (/TAS) P10242 (/TAS) P10242 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P06876 (/IDA) P51960 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P10243 (/ISS) Q05935 (/ISS)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
2 P10242 (/NAS) P10242 (/NAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P10243 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P06876 (/IDA)
Showing 1 to 7 of 7 entries
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