The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 34: HTH-type transcriptional repressor FabR
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
90 |
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
(80 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
7 | Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
7 | Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
7 | Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
7 | Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
7 | Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
90 |
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
P0ACU5 (/IDA)
(80 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) Q9KVJ2 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | Q9HUS3 (/EXP) Q9HUS3 (/EXP) Q9HUS3 (/EXP) Q9HUS3 (/EXP) Q9HUS3 (/EXP) Q9HUS3 (/EXP) Q9HUS3 (/EXP) |
|
Negative regulation of fatty acid metabolic process GO:0045922
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
|
7 | Q9HUS3 (/IMP) Q9HUS3 (/IMP) Q9HUS3 (/IMP) Q9HUS3 (/IMP) Q9HUS3 (/IMP) Q9HUS3 (/IMP) Q9HUS3 (/IMP) |
|
Positive regulation of melanin biosynthetic process GO:0048023
Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
|
1 | Q9HZ91 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
7 | Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) Q9HUS3 (/IDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
7 | Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) Q9HUS3 (/IPI) |