The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 22: ISWI chromatin-remodeling complex ATPase CHR11 iso...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 28 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
18 |
A5WUY4 (/IPI)
F4JAV9 (/IPI)
F4JY24 (/IPI)
F4JY24 (/IPI)
F4JY25 (/IPI)
O60264 (/IPI)
O60264 (/IPI)
P28370 (/IPI)
P28370 (/IPI)
P28370 (/IPI)
(8 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | O60264 (/ISA) O60264 (/ISA) P28370 (/ISA) P28370 (/ISA) P28370 (/ISA) P28370 (/ISA) |
|
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
|
6 | O60264 (/TAS) O60264 (/TAS) P28370 (/TAS) P28370 (/TAS) P28370 (/TAS) P28370 (/TAS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
5 | P28370 (/IPI) P28370 (/IPI) P28370 (/IPI) P28370 (/IPI) Q24368 (/IPI) |
|
Annealing helicase activity GO:0036310
Catalysis of the ATP-dependent rewinding of single-stranded DNA (ssDNA) to reform base pairs between strands. Often acts on ssDNA bubbles bound by replication protein A (RPA).
|
4 | P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | O60264 (/IDA) O60264 (/IDA) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | Q08773 (/IDA) Q08773 (/IDA) |
|
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
|
2 | Q08773 (/IDA) Q08773 (/IDA) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | O60264 (/IDA) O60264 (/IDA) |
|
DNA translocase activity GO:0015616
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule.
|
2 | Q08773 (/IDA) Q08773 (/IDA) |
Showing 1 to 10 of 28 entries
There are 82 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
9 | O60264 (/IDA) O60264 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) Q08773 (/IDA) Q08773 (/IDA) Q91ZW3 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
7 | P28370 (/IMP) P28370 (/IMP) P28370 (/IMP) P28370 (/IMP) P38144 (/IMP) P41877 (/IMP) Q24368 (/IMP) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
5 | P28370 (/IMP) P28370 (/IMP) P28370 (/IMP) P28370 (/IMP) Q6PGB8 (/IMP) |
|
Nucleosome positioning GO:0016584
Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.
|
5 | O60264 (/IDA) O60264 (/IDA) Q08773 (/IDA) Q08773 (/IDA) Q24368 (/IDA) |
|
ATP-dependent chromatin remodeling GO:0043044
Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.
|
5 | P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) Q24368 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | P28370 (/IMP) P28370 (/IMP) P28370 (/IMP) P28370 (/IMP) Q91ZW3 (/IMP) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
4 | P28370 (/ISS) P28370 (/ISS) P28370 (/ISS) P28370 (/ISS) |
|
Positive regulation of cellular response to heat GO:1900036
Any process that activates or increases the frequency, rate or extent of cellular response to heat.
|
4 | F4JY24 (/IMP) F4JY24 (/IMP) Q8RWY3 (/IMP) Q8RWY3 (/IMP) |
|
Cardiac ventricle development GO:0003231
The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
|
3 | A2RUY6 (/IMP) A5PLF2 (/IMP) B8A552 (/IMP) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
3 | O60264 (/IDA) O60264 (/IDA) Q24368 (/IDA) |
Showing 1 to 10 of 82 entries
There are 41 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
18 |
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
(8 more) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
18 |
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
A0A0A0MRP6 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
B7ZLQ5 (/IDA)
(8 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | F4JAV9 (/IDA) O60264 (/IDA) O60264 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) Q24368 (/IDA) Q91ZW3 (/IDA) |
|
NURF complex GO:0016589
An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.
|
7 | O60264 (/IDA) O60264 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) Q24368 (/IDA) |
|
CERF complex GO:0090537
An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters.
|
4 | P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) P28370 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P38144 (/HDA) Q08773 (/HDA) Q08773 (/HDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | O60264 (/TAS) O60264 (/TAS) Q91ZW3 (/TAS) |
|
RSF complex GO:0031213
An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).
|
3 | O60264 (/IPI) O60264 (/IPI) Q24368 (/IPI) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | P41877 (/IDA) Q6PGB8 (/IDA) |
|
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
|
2 | O60264 (/IDA) O60264 (/IDA) |
Showing 1 to 10 of 41 entries
