The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ubiquitin activating enzymes (Uba3). Chain: B, domain 2
".
FunFam 2: SUMO-activating enzyme subunit 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 20 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
SUMO activating enzyme activity GO:0019948
Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
|
6 | Q28GH3 (/ISS) Q642Q1 (/ISS) Q642Q1 (/ISS) Q7SXG4 (/ISS) Q7ZY60 (/ISS) Q9Z1F9 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q9UBT2 (/IPI) Q9UBT2 (/IPI) Q9Z1F9 (/IPI) |
|
SUMO activating enzyme activity GO:0019948
Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
|
3 | Q9UBT2 (/IDA) Q9UBT2 (/IDA) Q9Z1F9 (/IDA) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
2 | Q9UBT2 (/IMP) Q9UBT2 (/IMP) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | Q9UBT2 (/IMP) Q9UBT2 (/IMP) |
|
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
|
2 | Q9UBT2 (/TAS) Q9UBT2 (/TAS) |
|
SUMO activating enzyme activity GO:0019948
Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
|
2 | Q9UBT2 (/TAS) Q9UBT2 (/TAS) |
|
SUMO binding GO:0032183
Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
|
2 | Q9UBT2 (/IPI) Q9UBT2 (/IPI) |
|
Small protein activating enzyme binding GO:0044388
Interacting selectively and non-covalently with a small protein activating enzyme, such as ubiquitin-activating enzyme.
|
2 | Q9UBT2 (/IPI) Q9UBT2 (/IPI) |
|
Ubiquitin-like protein conjugating enzyme binding GO:0044390
Interacting selectively and non-covalently with a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme.
|
2 | Q9UBT2 (/IPI) Q9UBT2 (/IPI) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q9UBT2 (/IMP) Q9UBT2 (/IMP) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q9UBT2 (/IPI) Q9UBT2 (/IPI) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
1 | Q9Z1F9 (/ISO) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9Z1F9 (/ISO) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
1 | Q9Z1F9 (/IPI) |
|
SUMO activating enzyme activity GO:0019948
Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
|
1 | Q9Z1F9 (/ISO) |
|
SUMO binding GO:0032183
Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
|
1 | Q9Z1F9 (/ISO) |
|
Small protein activating enzyme binding GO:0044388
Interacting selectively and non-covalently with a small protein activating enzyme, such as ubiquitin-activating enzyme.
|
1 | Q9Z1F9 (/ISO) |
|
Ubiquitin-like protein conjugating enzyme binding GO:0044390
Interacting selectively and non-covalently with a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme.
|
1 | Q9Z1F9 (/ISO) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q9Z1F9 (/ISO) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein sumoylation GO:0016925
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
|
6 | Q28GH3 (/ISS) Q642Q1 (/ISS) Q642Q1 (/ISS) Q7SXG4 (/ISS) Q7ZY60 (/ISS) Q9Z1F9 (/ISS) |
|
Protein sumoylation GO:0016925
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
|
2 | Q9UBT2 (/IDA) Q9UBT2 (/IDA) |
|
Protein sumoylation GO:0016925
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
|
2 | Q9UBT2 (/IMP) Q9UBT2 (/IMP) |
|
Protein sumoylation GO:0016925
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
|
2 | Q9UBT2 (/TAS) Q9UBT2 (/TAS) |
|
Protein sumoylation GO:0016925
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
|
1 | Q9Z1F9 (/ISO) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
SUMO activating enzyme complex GO:0031510
A conserved heterodimeric complex with SUMO activating enzyme activity.
|
6 | Q28GH3 (/ISS) Q642Q1 (/ISS) Q642Q1 (/ISS) Q7SXG4 (/ISS) Q7ZY60 (/ISS) Q9Z1F9 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q9UBT2 (/IDA) Q9UBT2 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q9UBT2 (/TAS) Q9UBT2 (/TAS) |
|
SUMO activating enzyme complex GO:0031510
A conserved heterodimeric complex with SUMO activating enzyme activity.
|
2 | Q9UBT2 (/IDA) Q9UBT2 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9Z1F9 (/ISO) |
|
SUMO activating enzyme complex GO:0031510
A conserved heterodimeric complex with SUMO activating enzyme activity.
|
1 | Q9Z1F9 (/ISO) |
