The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MAN1, winged-helix domain
".
FunFam 9: Lap-Emerin-Man domain protein 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q10109 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q10109 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin silencing at rDNA GO:0000183
Repression of transcription of ribosomal DNA by altering the structure of chromatin.
|
1 | Q10109 (/IMP) |
|
Nuclear envelope organization GO:0006998
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
|
1 | Q10109 (/IMP) |
|
Chromatin silencing at silent mating-type cassette GO:0030466
Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
|
1 | Q10109 (/IMP) |
|
Chromatin silencing at centromere GO:0030702
Repression of transcription of centromeric DNA by altering the structure of chromatin.
|
1 | Q10109 (/IMP) |
|
Telomere tethering at nuclear periphery GO:0034398
The process in which a telomere is maintained in a specific location at the nuclear periphery.
|
1 | Q10109 (/IMP) |
|
Meiotic attachment of telomere to nuclear envelope GO:0070197
The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.
|
1 | Q10109 (/IMP) |
|
Nuclear inner membrane organization GO:0071765
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.
|
1 | Q10109 (/IGI) |
|
Centromere clustering at the mitotic nuclear envelope GO:0072766
A cellular localization process in which kinetochores/centromeres are coupled together at the nuclear periphery. This process is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei. In fission yeast this occurs at a location near the old mitotic spindle pole body.
|
1 | Q10109 (/IMP) |
|
Chromosome attachment to the nuclear envelope GO:0097240
The process in which chromatin is anchored to the nuclear envelope.
|
1 | Q10109 (/IMP) |
|
Chromatin silencing at subtelomere GO:0099114
Repression of transcription of subtelomeric DNA by altering the structure of chromatin.
|
1 | Q10109 (/IMP) |
|
Chromatin silencing at centromere outer repeat region GO:1990141
Repression of transcription of DNA at the outer repeat region of a regional centromere by altering the structure of chromatin.
|
1 | Q10109 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | Q10109 (/IDA) |
|
Integral component of nuclear inner membrane GO:0005639
The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q10109 (/IDA) |
|
Nuclear telomeric heterochromatin GO:0005724
Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus.
|
1 | Q10109 (/IDA) |
|
Nuclear pericentric heterochromatin GO:0031618
Nuclear heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.
|
1 | Q10109 (/IDA) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | Q10109 (/IDA) |
|
CENP-A containing chromatin GO:0061638
The specialized chromatin located the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.
|
1 | Q10109 (/EXP) |
|
Perinuclear endoplasmic reticulum GO:0097038
The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.
|
1 | Q10109 (/IDA) |
|
Nuclear rDNA heterochromatin GO:1902377
Any rDNA heterochromatin that is part of a nucleus.
|
1 | Q10109 (/IDA) |
|
Nuclear CENP-A containing chromatin GO:1904834
Any CENP-A containing chromatin that is part of nuclear chromatin.
|
1 | Q10109 (/IDA) |
|
Perinuclear endoplasmic reticulum membrane GO:1990578
The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.
|
1 | Q10109 (/HDA) |
