The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MAN1, winged-helix domain
".
FunFam 1: inner nuclear membrane protein Man1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q9Y2U8 (/IPI) Q9Y2U8 (/IPI) Q9Y2U8 (/IPI) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
3 | Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
3 | Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) |
|
Negative regulation of activin receptor signaling pathway GO:0032926
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
|
3 | Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) |
|
Cerebellum vasculature development GO:0061300
The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.
|
2 | B3DIX5 (/IMP) Q5TZH9 (/IMP) |
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | Q9WU40 (/IMP) |
|
Blood vessel endothelial cell migration involved in intussusceptive angiogenesis GO:0002044
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.
|
1 | Q9WU40 (/IMP) |
|
Nucleus organization GO:0006997
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
|
1 | Q9WU40 (/IMP) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
1 | Q9WU40 (/ISO) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q9WU40 (/ISO) |
|
Negative regulation of activin receptor signaling pathway GO:0032926
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
|
1 | Q9WU40 (/ISO) |
|
Skeletal muscle cell differentiation GO:0035914
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
|
1 | Q9WU40 (/IMP) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
1 | Q9WU40 (/IMP) |
|
Regulation of extracellular matrix organization GO:1903053
Any process that modulates the frequency, rate or extent of extracellular matrix organization.
|
1 | Q9WU40 (/IMP) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
6 | A0A024RBB9 (/IDA) A0A024RBB9 (/IDA) A0A024RBB9 (/IDA) Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
3 | Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) |
|
Integral component of nuclear inner membrane GO:0005639
The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | Q9Y2U8 (/TAS) Q9Y2U8 (/TAS) Q9Y2U8 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | Q9Y2U8 (/TAS) Q9Y2U8 (/TAS) Q9Y2U8 (/TAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) Q9Y2U8 (/IDA) |
|
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | Q9WU40 (/IDA) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | Q9WU40 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9WU40 (/ISO) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | Q9WU40 (/ISO) |
