CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
Superfamily | Vaccinia Virus protein VP39 |
Functional Family | Histone-lysine N-methyltransferase, H3 lysine-79 specific |
Enzyme Information
2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8TEK3
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (2)
P06897 |
H2A1_XENLA
Xenopus laevis
Histone H2A type 1
|
J3QS39 |
J3QS39_HUMAN
Homo sapiens
Polyubiquitin-B
|
PDB Structure
PDB | 6NOG |
External Links | |
Method | ELECTRON MICROSCOPY |
Organism | |
Primary Citation |
Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell
|