×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily 2.20.28.200
Functional Family NAD-dependent protein deacetylase sirtuin-6

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q8N6T7

UniProtKB Entries (1)

Q8N6T7
SIR6_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-6

PDB Structure

PDB 6HOY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Sirtuin 6 Inhibition by the Hydroxamate Trichostatin A: Implications for Protein Deacylase Drug Development.
You, W., Steegborn, C.
J.Med.Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...